Bioinformatický seminár

Mon 18 Apr. 2011, 17:20
I-9

Title: Paten et al. Cactus graphs for genome comparisons
Speaker: Marcel Kucharík

We introduce a data structure, analysis, and visualization scheme
called a cactus graph for comparing sets of related genomes. In common
with multi-break point graphs and A-Bruijn graphs, cactus graphs can
represent duplications and general genomic rearrangements, but
additionally, they naturally decompose the common substructures in a set
of related genomes into a hierarchy of chains that can be visualized as
two-dimensional multiple alignments and nets that can be visualized in
circular genome plots. Supplementary Material is available at
www.liebertonline.com/cmb .