Bioinformatický seminár

Tue 19 Feb. 2013, 17:20
I-9

Title: Livnat at al. (2010) Sex, mixability, and modularity
Speaker: Kubo Kováč

The assumption that different genetic elements can make separate contributions to
the same quantitative trait was originally made in order to reconcile biometry
and Mendelism and ever since has been used in population genetics, specifically
for the trait of fitness. Here we show that sex is responsible for the existence 
of separate genetic effects on fitness and, more generally, for the existence of 
a hierarchy of genetic evolutionary modules. Using the tools developed in the
process, we also demonstrate that in terms of their fitness effects, separation
and fusion of genes are associated with the increase and decrease of the
recombination rate between them, respectively. Implications for sex and evolution
theory are discussed.