Basic Information

NameCytochrome c oxidase subunit 2 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide II)
Uniprot IDP00410
Systematic gene nameQ0250
Standard gene nameCOX2
Gene namesCOX2 OXI1 Q0250
Description from SGDQ0250 COX2 SGDID:S000007281, Chr Mito from 73758-74513, Genome Release 64-3-1, Verified ORF, "Subunit II of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits"
Protein length251
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MLDLLRLQLT TFIMNDVPTP YACYFQDSAT PNQEGILELH DNIMFYLLVI
LGLVSWMLYT IVMTYSKNPI AYKYIKHGQT IEVIWTIFPA VILLIIAFPS
FILLYLCDEV ISPAMTIKAI GYQWYWKYEY SDFINDSGET VEFESYVIPD
ELLEEGQLRL LDTDTSMVVP VDTHIRFVVT AADVIHDFAI PSLGIKVDAT
PGRLNQVSAL IQREGVFYGA CSELCGTGHA NMPIKIEAVS LPKFLEWLNE
Q

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[166, Phos]Guo X, Niemi NM, Coon JJ, Pagliarini DJ (2017a) Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase. J Biol Chem 292:11751–11759. (Publication) (All modifications)
[166, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[208, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)