Basic Information

NamePutative COX1/OXI3 intron 2 protein
Uniprot IDP03876
Systematic gene nameQ0055
Standard gene nameAI2
Gene namesAI2 Q0055
Description from SGDQ0055 AI2 SGDID:S000007262, Chr Mito from 13818-13986,16435-18830, Genome Release 64-3-1, Verified ORF, "Reverse transcriptase required for splicing of the COX1 pre-mRNA; encoded by a mobile group II intron within the mitochondrial COX1 gene"
Protein length854
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
NSQLFNVLVV GHAVLMIFCA PFRLIYHCIE VLIDKHISVY SINENFTVSF
WFWLLVVTYM VFRYVNHMAY PVGANSTGTM ACHKSAGVKQ PAQGKNCPMA
RLTNSCKECL GFSLTPSHLG IVIHAYVLEE EVHELTKNES LALSKSWHLE
GCTSSNGKLR NTGLSERGNP GDNGVFMVPK FNLNKVRYFS TLSKLNARKE
DSLAYLTKIN TTDFSELNKL MENNHNKTET INTRILKLMS DIRMLLIAYN
KIKSKKGNMS KGSNNITLDG INISYLNKLS KDINTNMFKF SPVRRVEIPK
TSGGFRPLSV GNPREKIVQE SMRMMLEIIY NNSFSYYSHG FRPNLSCLTA
IIQCKNYMQY CNWFIKVDLN KCFDTIPHNM LINVLNERIK DKGFMDLLYK
LLRAGYVDKN NNYHNTTLGI PQGSVVSPIL CNIFLDKLDK YLENKFENEF
NTGNMSNRGR NPIYNSLSSK IYRCKLLSEK LKLIRLRDHY QRNMGSDKSF
KRAYFVRYAD DIIIGVMGSH NDCKNILNDI NNFLKENLGM SINMDKSVIK
HSKEGVSFLG YDVKVTPWEK RPYRMIKKGD NFIRVRHHTS LVVNAPIRSI
VMKLNKHGYC SHGILGKPRG VGRLIHEEMK TILMHYLAVG RGIMNYYRLA
TNFTTLRGRI TYILFYSCCL TLARKFKLNT VKKVILKFGK VLVDPHSKVS
FSIDDFKIRH KMNMTDSNYT PDEILDRYKY MLPRSLSLFS GICQICGSKH
DLEVHHVRTL NNAANKIKDD YLLGRMIKMN RKQITICKTC HFKVHQGKYN
GPGL

Legend

  • X SUMOylation
  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[303, SUMO]Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[490, SUMO]Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[522, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[522, Phos]Albuquerque, C.P., Smolka, M.B., Payne, S.H., Bafna, V., Eng, J., Zhou, H. (2008). A multidimensional chromatography technology for in-depth phosphoproteome analysis. Molecular and Cellular Proteomics 7(7):1389-1396. (Publication) (All modifications)
[522, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)