Basic Information
Name | Intron-encoded DNA endonuclease aI4 (DNA endonuclease I-SceII) [Cleaved into: Truncated non-functional cytochrome oxidase 1; DNA endonuclease aI4 (EC 3.1.-.-) (Intron-encoded endonuclease I-SceII)] |
Uniprot ID | P03878 |
Systematic gene name | Q0065 |
Standard gene name | AI4 |
Gene names | AI4 ENS2 I-SCEII Q0065 |
Description from SGD | Q0065 AI4 SGDID:S000007264, Chr Mito from 13818-13986,16435-16470,18954-18991,20508-21935, Genome Release 64-3-1, Verified ORF, "Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity" |
Protein length | 556 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
NSQLFNVLVV GHAVLMIFFL VMPALIGGFG NYLLPLMIGA TDTAFPRINN
IAFWVLPMGL VCLVTSTLVE SGAGTGWTVY PPLSSIQAHS GPSVDLAIFA
LHLTSISSLL GAINFIVTTL NMRTNGMTMH KLPLFVWSIF ITAFLLLLSL
PVLSAGITML LLDRNFNTSF FEVSGGGDPI LYEHLFWFFG QTVATIIMLM
MYNDMHFSKC WKLLKKWITN IMSTLFKALF VKMFMSYNNQ QDKMMNNTML
KKDNIKRSSE TTRKMLNNSM NKKFNQWLAG LIDGDGYFGI VSKKYVSLEI
TVALEDEMAL KEIQNKFGGS IKLRSGVKAI RYRLTNKTGM IKLINAVNGN
IRNTKRLVQF NKVCILLGID FIYPIKLTKD NSWFVGFFDA DGTINYSFKN
NHPQLTISVT NKYLQDVQEY KNILGGNIYF DKSQNGYYKW SIQSKDMVLN
FINDYIKMNP SRTTKMNKLY LSKEFYNLKE LKAYNKSSDS MQYKAWLNFE
NKWKNK
NSQLFNVLVV GHAVLMIFFL VMPALIGGFG NYLLPLMIGA TDTAFPRINN
IAFWVLPMGL VCLVTSTLVE SGAGTGWTVY PPLSSIQAHS GPSVDLAIFA
LHLTSISSLL GAINFIVTTL NMRTNGMTMH KLPLFVWSIF ITAFLLLLSL
PVLSAGITML LLDRNFNTSF FEVSGGGDPI LYEHLFWFFG QTVATIIMLM
MYNDMHFSKC WKLLKKWITN IMSTLFKALF VKMFMSYNNQ QDKMMNNTML
KKDNIKRSSE TTRKMLNNSM NKKFNQWLAG LIDGDGYFGI VSKKYVSLEI
TVALEDEMAL KEIQNKFGGS IKLRSGVKAI RYRLTNKTGM IKLINAVNGN
IRNTKRLVQF NKVCILLGID FIYPIKLTKD NSWFVGFFDA DGTINYSFKN
NHPQLTISVT NKYLQDVQEY KNILGGNIYF DKSQNGYYKW SIQSKDMVLN
FINDYIKMNP SRTTKMNKLY LSKEFYNLKE LKAYNKSSDS MQYKAWLNFE
NKWKNK
Legend
- X K-Succinylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[529, K-succ] | Weinert, B.T., Schölz, C., Wagner, S.A., et al. (2013). Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Reports, 4(4), 842-851. (Publication) (All modifications) |
[529, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |