P04039 y-mtPTM: Yeast Mitochondrial PTM Database

Basic Information

Name	Cytochrome c oxidase subunit 8, mitochondrial (Cytochrome c oxidase polypeptide VIII)
Uniprot ID	P04039
Systematic gene name	YLR395C
Standard gene name	COX8
Gene names	COX8 YLR395C L8084.14
Description from SGD	YLR395C COX8 SGDID:S000004387, Chr XII from 909965-909729, Genome Release 64-3-1, reverse complement, Verified ORF, "Subunit VIII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain"
Protein length	78
Download	sequence (fasta, from Uniprot), modifications (csv format)
Database links	Uniprot, SGD, TheCellVision.org, FungiDB

Sequence

MLCQQMIRTT AKRSSNIMTR PIIMKRSVHF KDGVYENIPF KVKGRKTPYA
LSHFGFFAIG FAVPFVACYV QLKKSGAF

Legend

X K-Succinylation

Structure

Structure visualized

Loading structure by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database. id="glmol01_src" style="display: none;"> -35.417 -30.817 -3.978 1.00 61.81 N -34.343 -31.136 -4.954 1.00 61.81 C -33.925 -29.941 -5.828 1.00 61.81 C -32.734 -29.803 -6.077 1.00 61.81 O -34.688 -32.375 -5.790 1.00 61.81 C -34.821 -33.614 -4.892 1.00 61.81 C -34.880 -35.162 -5.816 1.00 61.81 S -35.225 -36.339 -4.477 1.00 61.81 C -34.835 -29.031 -6.219 1.00 76.66 N -34.518 -27.823 -7.015 1.00 76.66 C -33.373 -26.949 -6.459 1.00 76.66 C -32.526 -26.480 -7.215 1.00 76.66 O -35.795 -26.957 -7.141 1.00 76.66 C -36.458 -27.004 -8.537 1.00 76.66 C -37.840 -27.653 -8.464 1.00 76.66 C -36.611 -25.592 -9.101 1.00 76.66 C -33.306 -26.758 -5.138 1.00 78.30 N -32.285 -25.900 -4.523 1.00 78.30 C -30.852 -26.424 -4.759 1.00 78.30 C -29.940 -25.659 -5.066 1.00 78.30 O -32.630 -25.740 -3.033 1.00 78.30 C -31.819 -24.249 -2.404 1.00 78.30 S -30.660 -27.748 -4.733 1.00 72.90 N -29.359 -28.364 -5.019 1.00 72.90 C -28.953 -28.207 -6.492 1.00 72.90 C -27.769 -28.039 -6.788 1.00 72.90 O -29.396 -29.851 -4.645 1.00 72.90 C -29.488 -30.099 -3.130 1.00 72.90 C -29.549 -31.588 -2.799 1.00 72.90 C -29.357 -31.973 -1.558 1.00 72.90 N -29.791 -32.427 -3.649 1.00 72.90 O -29.915 -28.230 -7.420 1.00 73.77 N -29.648 -27.981 -8.839 1.00 73.77 C -29.253 -26.520 -9.083 1.00 73.77 C -28.268 -26.284 -9.782 1.00 73.77 O -30.861 -28.378 -9.687 1.00 73.77 C -31.060 -29.903 -9.731 1.00 73.77 C -32.317 -30.296 -10.503 1.00 73.77 C -32.380 -31.482 -11.067 1.00 73.77 N -33.278 -29.554 -10.586 1.00 73.77 O -29.928 -25.558 -8.439 1.00 73.38 N -29.543 -24.144 -8.514 1.00 73.38 C -28.119 -23.916 -8.000 1.00 73.38 C -27.307 -23.349 -8.727 1.00 73.38 O -30.533 -23.238 -7.770 1.00 73.38 C -31.784 -22.965 -8.609 1.00 73.38 C -32.727 -21.517 -8.066 1.00 73.38 S -33.428 -22.121 -6.510 1.00 73.38 C -27.766 -24.446 -6.821 1.00 76.52 N -26.404 -24.335 -6.263 1.00 76.52 C -25.358 -24.885 -7.246 1.00 76.52 C -24.333 -24.244 -7.483 1.00 76.52 O -26.331 -25.035 -4.883 1.00 76.52 C -27.178 -24.261 -3.845 1.00 76.52 C -24.877 -25.148 -4.383 1.00 76.52 C -27.458 -25.051 -2.560 1.00 76.52 C -25.629 -26.029 -7.892 1.00 70.63 N -24.731 -26.602 -8.911 1.00 70.63 C -24.616 -25.724 -10.159 1.00 70.63 C -23.518 -25.603 -10.703 1.00 70.63 O -25.182 -28.024 -9.279 1.00 70.63 C -24.883 -29.040 -8.167 1.00 70.63 C -25.395 -30.430 -8.570 1.00 70.63 C -25.200 -31.416 -7.488 1.00 70.63 N -24.951 -32.712 -7.611 1.00 70.63 C -24.816 -33.295 -8.771 1.00 70.63 N1+ -24.834 -33.462 -6.552 1.00 70.63 N -25.702 -25.101 -10.621 1.00 69.88 N -25.644 -24.181 -11.772 1.00 69.88 C -24.897 -22.888 -11.451 1.00 69.88 C -24.105 -22.429 -12.274 1.00 69.88 O -27.025 -23.864 -12.360 1.00 69.88 C -27.640 -25.088 -13.037 1.00 69.88 C -27.949 -23.401 -11.407 1.00 69.88 O -25.054 -22.341 -10.242 1.00 66.75 N -24.340 -21.134 -9.804 1.00 66.75 C -22.848 -21.416 -9.624 1.00 66.75 C -22.018 -20.638 -10.096 1.00 66.75 O -24.943 -20.564 -8.508 1.00 66.75 C -24.636 -19.078 -8.350 1.00 66.75 C -26.344 -20.659 -8.538 1.00 66.75 O -22.494 -22.577 -9.058 1.00 64.07 N -21.105 -23.020 -8.930 1.00 64.07 C -20.409 -23.154 -10.299 1.00 64.07 C -19.309 -22.635 -10.487 1.00 64.07 O -21.082 -24.335 -8.142 1.00 64.07 C -21.074 -23.762 -11.295 1.00 62.64 N -20.537 -23.879 -12.666 1.00 62.64 C -20.429 -22.534 -13.392 1.00 62.64 C -19.525 -22.339 -14.203 1.00 62.64 O -21.391 -24.855 -13.488 1.00 62.64 C -21.177 -26.320 -13.079 1.00 62.64 C -21.992 -27.250 -13.989 1.00 62.64 C -21.744 -28.718 -13.624 1.00 62.64 C -22.378 -29.643 -14.599 1.00 62.64 N1+ -21.333 -21.584 -13.123 1.00 59.86 N -21.248 -20.237 -13.710 1.00 59.86 C -20.061 -19.460 -13.135 1.00 59.86 C -19.375 -18.773 -13.887 1.00 59.86 O -22.591 -19.505 -13.548 1.00 59.86 C -22.794 -18.439 -14.636 1.00 59.86 C -24.180 -17.794 -14.504 1.00 59.86 C -24.491 -16.906 -15.644 1.00 59.86 N -25.599 -16.196 -15.801 1.00 59.86 C -26.549 -16.187 -14.907 1.00 59.86 N1+ -25.778 -15.472 -16.870 1.00 59.86 N -19.769 -19.637 -11.845 1.00 59.88 N -18.641 -18.981 -11.175 1.00 59.88 C -17.282 -19.426 -11.727 1.00 59.88 C -16.414 -18.586 -11.962 1.00 59.88 O -18.720 -19.233 -9.667 1.00 59.88 C -17.954 -18.265 -8.984 1.00 59.88 O -17.097 -20.719 -12.019 1.00 61.07 N -15.833 -21.217 -12.586 1.00 61.07 C -15.585 -20.724 -14.017 1.00 61.07 C -14.448 -20.439 -14.389 1.00 61.07 O -15.789 -22.748 -12.527 1.00 61.07 C -16.847 -23.330 -13.267 1.00 61.07 O -16.645 -20.573 -14.817 1.00 57.69 N -16.537 -20.121 -16.207 1.00 57.69 C -16.336 -18.604 -16.340 1.00 57.69 C -15.787 -18.149 -17.340 1.00 57.69 O -17.776 -20.600 -16.981 1.00 57.69 C -17.770 -22.099 -17.229 1.00 57.69 C -18.886 -22.660 -17.628 1.00 57.69 N -16.774 -22.787 -17.095 1.00 57.69 O -16.757 -17.804 -15.357 1.00 60.20 N -16.487 -16.357 -15.352 1.00 60.20 C -15.006 -16.090 -15.044 1.00 60.20 C -14.406 -15.195 -15.637 1.00 60.20 O -17.457 -15.641 -14.385 1.00 60.20 C -18.891 -15.686 -14.968 1.00 60.20 C -17.041 -14.176 -14.147 1.00 60.20 C -19.986 -15.330 -13.953 1.00 60.20 C -14.392 -16.901 -14.180 1.00 58.31 N -13.014 -16.688 -13.732 1.00 58.31 C -11.957 -17.040 -14.796 1.00 58.31 C -10.888 -16.434 -14.825 1.00 58.31 O -12.818 -17.468 -12.426 1.00 58.31 C -11.601 -16.985 -11.637 1.00 58.31 C -11.482 -17.758 -10.005 1.00 58.31 S -9.878 -17.110 -9.467 1.00 58.31 C -12.246 -17.973 -15.708 1.00 58.56 N -11.276 -18.453 -16.713 1.00 58.56 C -11.282 -17.675 -18.032 1.00 58.56 C -10.248 -17.589 -18.696 1.00 58.56 O -11.485 -19.947 -16.988 1.00 58.56 C -10.995 -20.801 -15.820 1.00 58.56 C -12.859 -20.218 -17.158 1.00 58.56 O -12.400 -17.043 -18.415 1.00 58.49 N -12.510 -16.304 -19.691 1.00 58.49 C -11.539 -15.125 -19.869 1.00 58.49 C -11.025 -14.987 -20.980 1.00 58.49 O -13.961 -15.867 -19.935 1.00 58.49 C -14.828 -17.082 -20.295 1.00 58.49 C -16.296 -16.697 -20.511 1.00 58.49 C -16.555 -16.347 -21.926 1.00 58.49 N -17.302 -17.016 -22.791 1.00 58.49 C -17.983 -18.076 -22.452 1.00 58.49 N1+ -17.376 -16.632 -24.034 1.00 58.49 N -11.215 -14.294 -18.857 1.00 60.80 N -10.314 -13.163 -19.085 1.00 60.80 C -8.844 -13.574 -19.261 1.00 60.80 C -8.048 -12.765 -19.729 1.00 60.80 O -10.522 -12.234 -17.886 1.00 60.80 C -10.951 -13.179 -16.766 1.00 60.80 C -11.753 -14.248 -17.500 1.00 60.80 C -8.460 -14.804 -18.901 1.00 60.84 N -7.057 -15.246 -18.943 1.00 60.84 C -6.627 -15.591 -20.377 1.00 60.84 C -5.496 -15.303 -20.761 1.00 60.84 O -6.835 -16.408 -17.942 1.00 60.84 C -7.145 -15.936 -16.498 1.00 60.84 C -5.393 -16.947 -18.017 1.00 60.84 C -7.191 -17.064 -15.460 1.00 60.84 C -7.526 -16.153 -21.194 1.00 60.01 N -7.186 -16.615 -22.550 1.00 60.01 C -7.108 -15.445 -23.545 1.00 60.01 C -6.155 -15.374 -24.314 1.00 60.01 O -8.135 -17.755 -22.995 1.00 60.01 C -7.982 -18.964 -22.037 1.00 60.01 C -7.842 -18.175 -24.449 1.00 60.01 C -8.968 -20.111 -22.291 1.00 60.01 C -8.027 -14.471 -23.486 1.00 61.21 N -8.001 -13.318 -24.409 1.00 61.21 C -6.794 -12.390 -24.195 1.00 61.21 C -6.359 -11.721 -25.126 1.00 61.21 O -9.302 -12.507 -24.308 1.00 61.21 C -10.504 -13.269 -24.875 1.00 61.21 C -12.058 -12.331 -24.870 1.00 61.21 S -11.835 -11.295 -26.346 1.00 61.21 C -6.216 -12.362 -22.987 1.00 61.58 N -5.059 -11.509 -22.678 1.00 61.58 C -3.749 -11.980 -23.309 1.00 61.58 C -2.820 -11.188 -23.386 1.00 61.58 O -4.908 -11.365 -21.158 1.00 61.58 C -5.927 -10.368 -20.594 1.00 61.58 C -5.735 -10.218 -19.082 1.00 61.58 C -6.718 -9.181 -18.532 1.00 61.58 C -6.437 -8.874 -17.108 1.00 61.58 N1+ -3.654 -13.235 -23.763 1.00 65.39 N -2.408 -13.771 -24.340 1.00 65.39 C -2.139 -13.317 -25.777 1.00 65.39 C -1.000 -13.400 -26.211 1.00 65.39 O -2.381 -15.301 -24.225 1.00 65.39 C -2.173 -15.750 -22.773 1.00 65.39 C -1.991 -17.269 -22.714 1.00 65.39 C -1.611 -17.714 -21.360 1.00 65.39 N -1.749 -18.932 -20.865 1.00 65.39 C -2.298 -19.897 -21.549 1.00 65.39 N1+ -1.324 -19.207 -19.664 1.00 65.39 N -3.148 -12.829 -26.498 1.00 76.00 N -3.015 -12.423 -27.909 1.00 76.00 C -2.705 -10.935 -28.110 1.00 76.00 C -2.725 -10.462 -29.242 1.00 76.00 O -4.271 -12.822 -28.689 1.00 76.00 C -4.480 -14.219 -28.589 1.00 76.00 O -2.441 -10.182 -27.039 1.00 84.35 N -2.152 -8.742 -27.107 1.00 84.35 C -0.668 -8.511 -26.837 1.00 84.35 C -0.144 -8.984 -25.831 1.00 84.35 O -3.043 -7.943 -26.136 1.00 84.35 C -2.820 -6.432 -26.290 1.00 84.35 C -4.535 -8.222 -26.385 1.00 84.35 C 0.006 -7.773 -27.721 1.00 87.69 N 1.372 -7.310 -27.482 1.00 87.69 C 1.336 -6.138 -26.491 1.00 87.69 C 0.839 -5.055 -26.810 1.00 87.69 O 2.037 -6.946 -28.816 1.00 87.69 C 3.498 -6.599 -28.677 1.00 87.69 C 4.022 -5.348 -28.497 1.00 87.69 C 4.559 -7.480 -28.702 1.00 87.69 N 5.691 -6.772 -28.534 1.00 87.69 C 5.410 -5.465 -28.437 1.00 87.69 N 1.809 -6.374 -25.270 1.00 88.90 N 1.978 -5.329 -24.263 1.00 88.90 C 3.291 -4.585 -24.493 1.00 88.90 C 4.213 -5.118 -25.099 1.00 88.90 O 1.883 -5.924 -22.853 1.00 88.90 C 0.528 -6.541 -22.565 1.00 88.90 C -0.587 -5.715 -22.329 1.00 88.90 C 0.367 -7.938 -22.593 1.00 88.90 C -1.859 -6.283 -22.128 1.00 88.90 C -0.902 -8.506 -22.390 1.00 88.90 C -2.016 -7.680 -22.161 1.00 88.90 C 3.365 -3.339 -24.025 1.00 90.59 N 4.592 -2.549 -24.128 1.00 90.59 C 5.654 -3.111 -23.192 1.00 90.59 C 5.374 -3.343 -22.017 1.00 90.59 O 4.328 -1.085 -23.778 1.00 90.59 C 3.395 -0.404 -24.781 1.00 90.59 C 3.179 1.034 -24.321 1.00 90.59 C 2.263 1.773 -25.289 1.00 90.59 C 2.069 3.155 -24.802 1.00 90.59 N1+ 6.870 -3.224 -23.702 1.00 90.75 N 8.050 -3.508 -22.896 1.00 90.75 C 8.648 -2.209 -22.327 1.00 90.75 C 8.606 -1.152 -22.961 1.00 90.75 O 9.064 -4.296 -23.734 1.00 90.75 C 8.524 -5.673 -24.137 1.00 90.75 C 8.070 -6.395 -23.220 1.00 90.75 O 8.593 -5.988 -25.344 1.00 90.75 O1- 9.216 -2.273 -21.118 1.00 92.20 N 9.927 -1.148 -20.504 1.00 92.20 C 9.888 -1.125 -18.973 1.00 92.20 C 9.060 -1.774 -18.341 1.00 92.20 O 10.772 -0.319 -18.370 1.00 94.99 N 11.008 -0.248 -16.907 1.00 94.99 C 9.768 0.151 -16.090 1.00 94.99 C 9.663 -0.224 -14.927 1.00 94.99 O 12.166 0.735 -16.609 1.00 94.99 C 12.471 0.908 -15.113 1.00 94.99 C 13.468 0.278 -17.284 1.00 94.99 C 8.845 0.924 -16.670 1.00 93.89 N 7.624 1.398 -15.999 1.00 93.89 C 6.329 0.944 -16.686 1.00 93.89 C 5.248 1.357 -16.271 1.00 93.89 O 7.663 2.930 -15.864 1.00 93.89 C 8.749 3.483 -14.960 1.00 93.89 C 8.749 3.160 -13.590 1.00 93.89 C 9.740 4.338 -15.477 1.00 93.89 C 9.721 3.702 -12.729 1.00 93.89 C 10.713 4.889 -14.621 1.00 93.89 C 10.700 4.576 -13.245 1.00 93.89 C 11.623 5.132 -12.418 1.00 93.89 O 6.418 0.113 -17.726 1.00 93.74 N 5.246 -0.416 -18.443 1.00 93.74 C 4.745 -1.735 -17.821 1.00 93.74 C 3.641 -2.192 -18.103 1.00 93.74 O 5.580 -0.577 -19.936 1.00 93.74 C 6.004 0.728 -20.642 1.00 93.74 C 4.924 1.830 -20.680 1.00 93.74 C 5.283 3.020 -20.514 1.00 93.74 O 3.736 1.523 -20.941 1.00 93.74 O1- 5.528 -2.321 -16.907 1.00 92.25 N 5.211 -3.539 -16.158 1.00 92.25 C 4.369 -3.297 -14.889 1.00 92.25 C 4.045 -4.245 -14.173 1.00 92.25 O 6.531 -4.249 -15.809 1.00 92.25 C 7.361 -3.472 -14.798 1.00 92.25 C 7.956 -4.132 -13.834 1.00 92.25 N 7.467 -2.259 -14.843 1.00 92.25 O 4.039 -2.042 -14.579 1.00 95.04 N 3.283 -1.648 -13.387 1.00 95.04 C 1.960 -0.979 -13.775 1.00 95.04 C 1.899 -0.222 -14.742 1.00 95.04 O 4.119 -0.764 -12.437 1.00 95.04 C 4.792 0.402 -13.190 1.00 95.04 C 5.148 -1.635 -11.697 1.00 95.04 C 5.481 1.415 -12.281 1.00 95.04 C 0.879 -1.188 -13.001 1.00 93.53 N -0.450 -0.686 -13.351 1.00 93.53 C -0.637 0.816 -13.072 1.00 93.53 C -1.746 1.335 -13.186 1.00 93.53 O -1.414 -1.563 -12.548 1.00 93.53 C -0.618 -1.893 -11.287 1.00 93.53 C 0.814 -2.014 -11.802 1.00 93.53 C 0.419 1.532 -12.681 1.00 95.47 N 0.369 2.954 -12.368 1.00 95.47 C 1.523 3.706 -13.029 1.00 95.47 C 2.677 3.292 -13.019 1.00 95.47 O 0.326 3.173 -10.849 1.00 95.47 C 1.428 2.478 -10.072 1.00 95.47 C 1.196 1.211 -9.505 1.00 95.47 C 2.691 3.082 -9.928 1.00 95.47 C 2.223 0.543 -8.817 1.00 95.47 C 3.712 2.421 -9.225 1.00 95.47 C 3.483 1.149 -8.678 1.00 95.47 C 1.207 4.879 -13.577 1.00 95.25 N 2.189 5.751 -14.223 1.00 95.25 C 3.085 6.411 -13.173 1.00 95.25 C 2.560 7.078 -12.285 1.00 95.25 O 1.421 6.740 -15.116 1.00 95.25 C 2.329 7.749 -15.823 1.00 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References

[41, K-succ]

Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)