Basic Information

NameTryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) (Tryptophanyl-tRNA synthetase) (TrpRS)
Uniprot IDP04803
Systematic gene nameYDR268W
Standard gene nameMSW1
Gene namesMSW1 MSW YDR268W D9954.7
Description from SGDYDR268W MSW1 SGDID:S000002676, Chr IV from 1004004-1005143, Genome Release 64-3-1, Verified ORF, "Mitochondrial tryptophanyl-tRNA synthetase"
Protein length379
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSNKQAVLKL ISKRWISTVQ RADFKLNSEA LHSNATVFSM IQPTGCFHLG
NYLGATRVWT DLCELKQPGQ ELIFGVADLH AITVPKPDGE MFRKFRHEAV
ASILAVGVDP EKASVIYQSA IPQHSELHWL LSTLASMGLL NRMTQWKSKS
NIKQSTNGDY LVNDSDVGKV RLGLFSYPVL QAADILLYKS THVPVGDDQS
QHLELTRHLA EKFNKMYKKN FFPKPVTMLA QTKKVLSLST PEKKMSKSDP
NHDSVIFLND EPKAIQKKIR KALTDSISDR FYYDPVERPG VSNLINIVSG
IQRKSIEDVV EDVSRFNNYR DFKDYVSEVI IEELKGPRTE FEKYINEPTY
LHSVVESGMR KAREKAAKNL ADIHKIMGF

Legend

  • X Multiple modifications

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[212, K-succ]Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)
[212, K-acetyl]Henriksen, P., Wagner, S. A., Weinert, B. T., et al. (2012). Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Molecular & Cellular Proteomics, 11(11), 1510-1522. (Publication) (All modifications)