P06182

Name	Cytochrome c heme lyase (CCHL) (EC 4.4.1.17) (Holocytochrome-c synthase)
Uniprot ID	P06182
Systematic gene name	YAL039C
Standard gene name	CYC3
Gene names	CYC3 YAL039C
Description from SGD	YAL039C CYC3 SGDID:S000000037, Chr I from 69525-68716, Genome Release 64-3-1, reverse complement, Verified ORF, "Cytochrome c heme lyase (holocytochrome c synthase); attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in mitochondrial intermembrane space; human homolog HCCS implicated in microphthalmia with linear skin defects (MLS), and can complement yeast null mutant"
Protein length	269
Download	sequence (fasta, from Uniprot), modifications (csv format)
Database links	Uniprot, SGD, TheCellVision.org, FungiDB

MGWFWADQKT TGKDIGGAAV SSMSGCPVMH ESSSSSPPSS ECPVMQGDND
RINPLNNMPE LAASKQPGQK MDLPVDRTIS SIPKSPDSNE FWEYPSPQQM
YNAMVRKGKI GGSGEVAEDA VESMVQVHNF LNEGCWQEVL EWEKPHTDES
HVQPKLLKFM GKPGVLSPRA RWMHLCGLLF PSHFSQELPF DRHDWIVLRG
ERKAEQQPPT FKEVRYVLDF YGGPDDENGM PTFHVDVRPA LDSLDNAKDR
MTRFLDRMIS GPSSSSSAP

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[70, Ubi]	Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[70, SUMO]	Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications)
[80, Phos]	Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[80, Phos]	Zhou, X., Li, W., Liu, Y., Amon, A. (2021. Cross-compartment signal propagation in the mitotic exit network. Elife 10:e63645. (Publication) (All modifications)
[81, Phos]	Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[81, Phos]	Zhou, X., Li, W., Liu, Y., Amon, A. (2021. Cross-compartment signal propagation in the mitotic exit network. Elife 10:e63645. (Publication) (All modifications)
[158, K-succ]	Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)
[162, K-succ]	Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)