Basic Information

NameMitochondrial RNA-splicing protein MRS1
Uniprot IDP07266
Systematic gene nameYIR021W
Standard gene nameMRS1
Gene namesMRS1 PET157 YIR021W
Description from SGDYIR021W MRS1 SGDID:S000001460, Chr IX from 397294-398385, Genome Release 64-3-1, Verified ORF, "Splicing protein; required for splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA; MRS1 has a paralog, CCE1, that arose from the whole genome duplication"
Protein length363
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSPKNITRSV IPAIDLYCRK ANFKTLKSLS MILGSKKEWY DTKKAPLRTF
LVSRCGIFEQ LRGRLVEDGK VNLFSVFLTN DSFSFCKMTV DDKFNTSLVD
WQKIPFDSTF ATDRRQNISL LPVDTLFATE KIISILGVSP NMTNLVSIER
ERSDLVDFNC KLQSNILEHL LYAKCQGVYV TSTNEKARLL AAVCNPEFID
TFWCELTPIR VSLKENPSIS VPREYQMYDP VVRATIKEVV TKRLLRSAFD
NDIDPLMCLH LDKGWKLKFP ILSSTTGLNF SLKDCLSLDT GKDASDMTEV
FLATMESSKV LRTYSNLVDI VMKDNGRLDS GVLKQFNDYV KQEKLNLQHF
QAGSSKFLKG AKI

Legend

  • X SUMOylation
  • X Phoshorylation
  • X K-Succinylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


Use imported representation

Loading structure from server... It may take a while.

If you believe something went wrong, please make sure PDB ID is correct.
Please also make sure that WebGL is enabled in your browser.

References

[27, SUMO]Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications)
[36, SUMO]Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications)
[153, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[237, SUMO]Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications)
[287, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[356, K-succ]Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)