Basic Information
Name | Mitochondrial RNA-splicing protein MRS1 |
Uniprot ID | P07266 |
Systematic gene name | YIR021W |
Standard gene name | MRS1 |
Gene names | MRS1 PET157 YIR021W |
Description from SGD | YIR021W MRS1 SGDID:S000001460, Chr IX from 397294-398385, Genome Release 64-3-1, Verified ORF, "Splicing protein; required for splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA; MRS1 has a paralog, CCE1, that arose from the whole genome duplication" |
Protein length | 363 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MSPKNITRSV IPAIDLYCRK ANFKTLKSLS MILGSKKEWY DTKKAPLRTF
LVSRCGIFEQ LRGRLVEDGK VNLFSVFLTN DSFSFCKMTV DDKFNTSLVD
WQKIPFDSTF ATDRRQNISL LPVDTLFATE KIISILGVSP NMTNLVSIER
ERSDLVDFNC KLQSNILEHL LYAKCQGVYV TSTNEKARLL AAVCNPEFID
TFWCELTPIR VSLKENPSIS VPREYQMYDP VVRATIKEVV TKRLLRSAFD
NDIDPLMCLH LDKGWKLKFP ILSSTTGLNF SLKDCLSLDT GKDASDMTEV
FLATMESSKV LRTYSNLVDI VMKDNGRLDS GVLKQFNDYV KQEKLNLQHF
QAGSSKFLKG AKI
LVSRCGIFEQ LRGRLVEDGK VNLFSVFLTN DSFSFCKMTV DDKFNTSLVD
WQKIPFDSTF ATDRRQNISL LPVDTLFATE KIISILGVSP NMTNLVSIER
ERSDLVDFNC KLQSNILEHL LYAKCQGVYV TSTNEKARLL AAVCNPEFID
TFWCELTPIR VSLKENPSIS VPREYQMYDP VVRATIKEVV TKRLLRSAFD
NDIDPLMCLH LDKGWKLKFP ILSSTTGLNF SLKDCLSLDT GKDASDMTEV
FLATMESSKV LRTYSNLVDI VMKDNGRLDS GVLKQFNDYV KQEKLNLQHF
QAGSSKFLKG AKI
Legend
- X SUMOylation
- X Phoshorylation
- X K-Succinylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[27, SUMO] | Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications) |
[36, SUMO] | Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications) |
[153, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[237, SUMO] | Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications) |
[287, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[356, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |