Basic Information
Name | tRNA dimethylallyltransferase (DMATase) (EC 2.5.1.75) (Isopentenyl-diphosphate: tRNA isopentenyltransferase) (IPP transferase) (IPPT) (tRNA isopentenyltransferase) (IPTase) |
Uniprot ID | P07884 |
Systematic gene name | YOR274W |
Standard gene name | MOD5 |
Gene names | MOD5 YOR274W |
Description from SGD | YOR274W MOD5 SGDID:S000005800, Chr XV from 837674-838960, Genome Release 64-3-1, Verified ORF, "Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; also has a role in tRNA gene-mediated silencing; gene encodes two isozymic forms; converts to a prion form, prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis; homolog of human TRIT1, a mutation in which is associated with severe combined respiratory chain defects" |
Protein length | 428 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MLKGPLKGCL NMSKKVIVIA GTTGVGKSQL SIQLAQKFNG EVINSDSMQV
YKDIPIITNK HPLQEREGIP HHVMNHVDWS EEYYSHRFET ECMNAIEDIH
RRGKIPIVVG GTHYYLQTLF NKRVDTKSSE RKLTRKQLDI LESTDPDVIY
NTLVKCDPDI ATKYHPNDYR RVQRMLEIYY KTGKKPSETF NEQKITLKFD
TLFLWLYSKP EPLFQRLDDR VDDMLERGAL QEIKQLYEYY SQNKFTPEQC
ENGVWQVIGF KEFLPWLTGK TDDNTVKLED CIERMKTRTR QYAKRQVKWI
KKMLIPDIKG DIYLLDATDL SQWDTNASQR AIAISNDFIS NRPIKQERAP
KALEELLSKG ETTMKKLDDW THYTCNVCRN ADGKNVVAIG EKYWKIHLGS
RRHKSNLKRN TRQADFEKWK INKKETVE
YKDIPIITNK HPLQEREGIP HHVMNHVDWS EEYYSHRFET ECMNAIEDIH
RRGKIPIVVG GTHYYLQTLF NKRVDTKSSE RKLTRKQLDI LESTDPDVIY
NTLVKCDPDI ATKYHPNDYR RVQRMLEIYY KTGKKPSETF NEQKITLKFD
TLFLWLYSKP EPLFQRLDDR VDDMLERGAL QEIKQLYEYY SQNKFTPEQC
ENGVWQVIGF KEFLPWLTGK TDDNTVKLED CIERMKTRTR QYAKRQVKWI
KKMLIPDIKG DIYLLDATDL SQWDTNASQR AIAISNDFIS NRPIKQERAP
KALEELLSKG ETTMKKLDDW THYTCNVCRN ADGKNVVAIG EKYWKIHLGS
RRHKSNLKRN TRQADFEKWK INKKETVE
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
No sources available.