Basic Information

NametRNA dimethylallyltransferase (DMATase) (EC 2.5.1.75) (Isopentenyl-diphosphate: tRNA isopentenyltransferase) (IPP transferase) (IPPT) (tRNA isopentenyltransferase) (IPTase)
Uniprot IDP07884
Systematic gene nameYOR274W
Standard gene nameMOD5
Gene namesMOD5 YOR274W
Description from SGDYOR274W MOD5 SGDID:S000005800, Chr XV from 837674-838960, Genome Release 64-3-1, Verified ORF, "Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; also has a role in tRNA gene-mediated silencing; gene encodes two isozymic forms; converts to a prion form, prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis; homolog of human TRIT1, a mutation in which is associated with severe combined respiratory chain defects"
Protein length428
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MLKGPLKGCL NMSKKVIVIA GTTGVGKSQL SIQLAQKFNG EVINSDSMQV
YKDIPIITNK HPLQEREGIP HHVMNHVDWS EEYYSHRFET ECMNAIEDIH
RRGKIPIVVG GTHYYLQTLF NKRVDTKSSE RKLTRKQLDI LESTDPDVIY
NTLVKCDPDI ATKYHPNDYR RVQRMLEIYY KTGKKPSETF NEQKITLKFD
TLFLWLYSKP EPLFQRLDDR VDDMLERGAL QEIKQLYEYY SQNKFTPEQC
ENGVWQVIGF KEFLPWLTGK TDDNTVKLED CIERMKTRTR QYAKRQVKWI
KKMLIPDIKG DIYLLDATDL SQWDTNASQR AIAISNDFIS NRPIKQERAP
KALEELLSKG ETTMKKLDDW THYTCNVCRN ADGKNVVAIG EKYWKIHLGS
RRHKSNLKRN TRQADFEKWK INKKETVE

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

No sources available.