Basic Information
Name | Mitochondrial nuclease (EC 3.1.30.-) |
Uniprot ID | P08466 |
Systematic gene name | YJL208C |
Standard gene name | NUC1 |
Gene names | NUC1 YJL208C HRE329 J0310 |
Description from SGD | YJL208C NUC1 SGDID:S000003744, Chr X from 41183-40194, Genome Release 64-3-1, reverse complement, Verified ORF, "Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; involved in fragmentation of genomic DNA during PND (programmed nuclear destruction); encodes ortholog of mammalian endoG" |
Protein length | 329 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MCSRILLSGL VGLGAGTGLT YLLLNKHSPT QIIETPYPPT QKPNSNIQSH
SFNVDPSGFF KYGFPGPIHD LQNREEFISC YNRQTQNPYW VLEHITPESL
AARNADRKNS FFKEDEVIPE KFRGKLRDYF RSGYDRGHQA PAADAKFSQQ
AMDDTFYLSN MCPQVGEGFN RDYWAHLEYF CRGLTKKYKS VRIVTGPLYL
PKKDPIDNKF RVNYEVIGNP PSIAVPTHFF KLIVAEAPTA NPAREDIAVA
AFVLPNEPIS NETKLTDFEV PIDALERSTG LELLQKVPPS KKKALCKEVN
CQIVVRDFSN AAIKQSKDVK LLPPPKKRN
SFNVDPSGFF KYGFPGPIHD LQNREEFISC YNRQTQNPYW VLEHITPESL
AARNADRKNS FFKEDEVIPE KFRGKLRDYF RSGYDRGHQA PAADAKFSQQ
AMDDTFYLSN MCPQVGEGFN RDYWAHLEYF CRGLTKKYKS VRIVTGPLYL
PKKDPIDNKF RVNYEVIGNP PSIAVPTHFF KLIVAEAPTA NPAREDIAVA
AFVLPNEPIS NETKLTDFEV PIDALERSTG LELLQKVPPS KKKALCKEVN
CQIVVRDFSN AAIKQSKDVK LLPPPKKRN
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[195, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[195, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[199, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[199, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |