Basic Information

NameMitochondrial transcription factor 1 (EC 2.1.1.-) (Mitochondrial transcription factor mtTFB) (Mitochondrial-specificity factor) (RF1023)
Uniprot IDP14908
Systematic gene nameYMR228W
Standard gene nameMTF1
Gene namesMTF1 YMR228W YM9959.10
Description from SGDYMR228W MTF1 SGDID:S000004841, Chr XIII from 724626-725651, Genome Release 64-3-1, Verified ORF, "Mitochondrial RNA polymerase specificity factor; has structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation"
Protein length341
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSVPIPGIKD ISKLKFFYGF KYLWNPTVYN KIFDKLDLTK TYKHPEELKV
LDLYPGVGIQ SAIFYNKYCP RQYSLLEKRS SLYKFLNAKF EGSPLQILKR
DPYDWSTYSN LIDEERIFVP EVQSSDHIND KFLTVANVTG EGSEGLIMQW
LSCIGNKNWL YRFGKVKMLL WMPSTTARKL LARPGMHSRS KCSVVREAFT
DTKLIAISDA NELKGFDSQC IEEWDPILFS AAEIWPTKGK PIALVEMDPI
DFDFDVDNWD YVTRHLMILK RTPLNTVMDS LGHGGQQYFN SRITDKDLLK
KCPIDLTNDE FIYLTKLFME WPFKPDILMD FVDMYQTEHS G

Legend

  • X Phoshorylation
  • X K-acetylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[12, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[12, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[84, K-acetyl]Henriksen, P., Wagner, S. A., Weinert, B. T., et al. (2012). Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Molecular & Cellular Proteomics, 11(11), 1510-1522. (Publication) (All modifications)
[93, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[93, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)