Basic Information

NameAcetylornithine aminotransferase, mitochondrial (ACOAT) (EC 2.6.1.11)
Uniprot IDP18544
Systematic gene nameYOL140W
Standard gene nameARG8
Gene namesARG8 YOL140W
Description from SGDYOL140W ARG8 SGDID:S000005500, Chr XV from 58759-60030, Genome Release 64-3-1, Verified ORF, "Acetylornithine aminotransferase; catalyzes the fourth step in the biosynthesis of the arginine precursor ornithine"
Protein length423
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MFKRYLSSTS SRRFTSILEE KAFQVTTYSR PEDLCITRGK NAKLYDDVNG
KEYIDFTAGI AVTALGHANP KVAEILHHQA NKLVHSSNLY FTKECLDLSE
KIVEKTKQFG GQHDASRVFL CNSGTEANEA ALKFAKKHGI MKNPSKQGIV
AFENSFHGRT MGALSVTWNS KYRTPFGDLV PHVSFLNLND EMTKLQSYIE
TKKDEIAGLI VEPIQGEGGV FPVEVEKLTG LKKICQDNDV IVIHDEIQCG
LGRSGKLWAH AYLPSEAHPD IFTSAKALGN GFPIAATIVN EKVNNALRVG
DHGTTYGGNP LACSVSNYVL DTIADEAFLK QVSKKSDILQ KRLREIQAKY
PNQIKTIRGK GLMLGAEFVE PPTEVIKKAR ELGLLIITAG KSTVRFVPAL
TIEDELIEEG MDAFEKAIEA VYA

Legend

  • X Phoshorylation
  • X SUMOylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[15, Phos]Ohlmeier S, Hiltunen JK, Bergmann U (2010) Protein phosphorylation in mitochondria - A study on fermentative and respiratory growth of Saccharomyces cerevisiae. Electrophoresis 31:2869–2881. (Publication) (All modifications)
[15, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[15, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[40, SUMO]Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications)