Basic Information
Name | Cell division control protein 42 (Suppressor of RHO3 protein 2) |
Uniprot ID | P19073 |
Systematic gene name | YLR229C |
Standard gene name | CDC42 |
Gene names | CDC42 SRO2 YLR229C L8083.13 |
Description from SGD | YLR229C CDC42 SGDID:S000004219, Chr XII from 604787-604212, Genome Release 64-3-1, reverse complement, Verified ORF, "Small rho-like GTPase; essential for establishment and maintenance of cell polarity; plays a role late in cell fusion via activation of key cell fusion regulator Fus2p; acts with ESCRT proteins at sites of nuclear envelope and ER fission; mutants have defects in the organization of actin and septins; human homolog CDC42 can complement yeast cdc42 mutant" |
Protein length | 191 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MQTLKCVVVG DGAVGKTCLL ISYTTNQFPA DYVPTVFDNY AVTVMIGDEP
YTLGLFDTAG QEDYDRLRPL SYPSTDVFLV CFSVISPPSF ENVKEKWFPE
VHHHCPGVPC LVVGTQIDLR DDKVIIEKLQ RQRLRPITSE QGSRLARELK
AVKYVECSAL TQRGLKNVFD EAIVAALEPP VIKKSKKCAI L
YTLGLFDTAG QEDYDRLRPL SYPSTDVFLV CFSVISPPSF ENVKEKWFPE
VHHHCPGVPC LVVGTQIDLR DDKVIIEKLQ RQRLRPITSE QGSRLARELK
AVKYVECSAL TQRGLKNVFD EAIVAALEPP VIKKSKKCAI L
Legend
- X Ubiquitination
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[123, Ubi] | Back, S., Gorman, A.W., Vogel, C., Silva, G.M. (2019). Site-specific K63 ubiquitinomics provides insights into translation regulation under stress. Journal of Proteome Research 18(1): 309-318. (Publication) (All modifications) |
[123, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[139, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[153, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[161, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |