Basic Information
| Name | Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.-) (Heme O synthase) |
| Uniprot ID | P21592 |
| Systematic gene name | YPL172C |
| Standard gene name | COX10 |
| Gene names | COX10 YPL172C |
| Description from SGD | YPL172C COX10 SGDID:S000006093, Chr XVI from 225741-224353, Genome Release 64-3-1, reverse complement, Verified ORF, "Heme A:farnesyltransferase; catalyzes first step in conversion of protoheme to heme A prosthetic group required for cytochrome c oxidase activity; human ortholog COX10 can complement yeast cox10 null mutant; human ortholog COX10 is associated with mitochondrial disorders" |
| Protein length | 462 |
| Download | sequence (fasta, from Uniprot), modifications (csv format) |
| Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MSYFPRTYAH LMRNVLAHNK GNIYLQIGTQ LHDTQIKIRF NGVRYISRNH
GGKQQHINTA PIEFTPNFGY GDRTSNCNKK VESTAMKTLR CTDDISTSSG
SEATTDASTQ LPFNVKLVDP MVRKSKRPSH AISEGLNMKT LKKKVIMPYL
QLTKPRLTIL VMLSAICSYA LSPYPASVNE LLCLTVGTTL CSGSANAINM
GREPEFDRQM VRTQARPVVR GDVTPTQAFE FAALIGTLGV SILYFGVNPT
VAILGASNIA LYGWAYTSMK RKHIINTWLG ALVGMVPPLM GWAAASPLSH
PGSWCLAGLL FAWQFPHFNT LSHNIRNEYK NAGYVMTAWK NPLLNARVSL
RYSILMFPLC FGLSYFNITD WYYQIDSGLI NAWLTFWAFK FYWQQRINYS
AKTLKDNVKF NKGLSVANIY ARKTFMASVL HLPAILILAI IHKKGRWDWI
YPGEAKRPQE RF
GGKQQHINTA PIEFTPNFGY GDRTSNCNKK VESTAMKTLR CTDDISTSSG
SEATTDASTQ LPFNVKLVDP MVRKSKRPSH AISEGLNMKT LKKKVIMPYL
QLTKPRLTIL VMLSAICSYA LSPYPASVNE LLCLTVGTTL CSGSANAINM
GREPEFDRQM VRTQARPVVR GDVTPTQAFE FAALIGTLGV SILYFGVNPT
VAILGASNIA LYGWAYTSMK RKHIINTWLG ALVGMVPPLM GWAAASPLSH
PGSWCLAGLL FAWQFPHFNT LSHNIRNEYK NAGYVMTAWK NPLLNARVSL
RYSILMFPLC FGLSYFNITD WYYQIDSGLI NAWLTFWAFK FYWQQRINYS
AKTLKDNVKF NKGLSVANIY ARKTFMASVL HLPAILILAI IHKKGRWDWI
YPGEAKRPQE RF
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
No sources available.