Basic Information

NameMitochondrial RNA-splicing protein MRS4
Uniprot IDP23500
Systematic gene nameYKR052C
Standard gene nameMRS4
Gene namesMRS4 YKR052C
Description from SGDYKR052C MRS4 SGDID:S000001760, Chr XI from 533464-532550, Genome Release 64-3-1, reverse complement, Verified ORF, "Iron transporter of the mitochondrial carrier family; mediates Fe2+ transport across the inner mitochondrial membrane; active under low-iron conditions; may transport other cations; protein abundance increases in response to DNA replication stress; MRS4 has a paralog, MRS3, that arose from the whole genome duplication"
Protein length304
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MNTSELSIAE EIDYEALPSH APLHSQLLAG AFAGIMEHSL MFPIDALKTR
VQAAGLNKAA STGMISQISK ISTMEGSMAL WKGVQSVILG AGPAHAVYFG
TYEFCKARLI SPEDMQTHQP MKTALSGTIA TIAADALMNP FDTVKQRLQL
DTNLRVWNVT KQIYQNEGFA AFYYSYPTTL AMNIPFAAFN FMIYESASKF
FNPQNSYNPL IHCLCGGISG ATCAALTTPL DCIKTVLQVR GSETVSIEIM
KDANTFGRAS RAILEVHGWK GFWRGLKPRI VANIPATAIS WTAYECAKHF
LMKN

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[152, Phos]Zhou, X., Li, W., Liu, Y., Amon, A. (2021. Cross-compartment signal propagation in the mitotic exit network. Elife 10:e63645. (Publication) (All modifications)