Basic Information

NameMitochondrial inner membrane i-AAA protease supercomplex subunit MGR1 (Mitochondrial genome-required protein 1)
Uniprot IDP25573
Systematic gene nameYCL044C
Standard gene nameMGR1
Gene namesMGR1 YCL044C YCL314 YCL44C
Description from SGDYCL044C MGR1 SGDID:S000000549, Chr III from 48364-47111, Genome Release 64-3-1, reverse complement, Verified ORF, "Subunit of the mitochondrial (mt) i-AAA protease supercomplex; i-AAA degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr3p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA"
Protein length417
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MAVFTPPSGN SNSTDHTHTQ DDHDKDDNDI KKFYIRPSLG LKLWGPLVPA
PDNLPGLYTL ITIQSAVGFF ALWRLRRLYK LPPPRRIATG THSDLSFGEL
PSEMIVNGKT KIKKDIADFP TLNRFSTTHG DIVLAPPPII PRQSRFVSVR
KLLWGLFGSL LLSQSLLELT RLNFLKYDPW CDEMKSVRDK KFFNNIVKYY
HEGIDPTKIK VKDAMNGTPL STNIPEVKQS VALARAQVEA QNPIIKWFGP
LEYKPMSFNE YLNRMEFHLD MFEFFQNKRN IRENSIELIN SISHNPQSSS
TGLEGLSESK KLHLQNVEKR LHFLASSGDS ISAPVKKRSS TTLSRGVILP
HDTKGPQDID LDTIRSLYDP WMTLALETSL SIKFIPTTMP SHTKTPTSTD
QPLPGPTPKA LTNEKTH

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[126, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[127, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[128, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[341, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[341, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[342, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[342, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)