Basic Information
| Name | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase) (PGP synthase) |
| Uniprot ID | P25578 |
| Systematic gene name | YCL004W |
| Standard gene name | PGS1 |
| Gene names | PGS1 PEL1 YCL004W YCL003W YCL3W YCL4W |
| Description from SGD | YCL004W PGS1 SGDID:S000000510, Chr III from 109105-110670, Genome Release 64-3-1, Verified ORF, "Phosphatidylglycerolphosphate synthase; catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis" |
| Protein length | 521 |
| Download | sequence (fasta, from Uniprot), modifications (csv format) |
| Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MTTRLLQLTR PHYRLLSLPL QKPFNIKRQM SAANPSPFGN YLNTITKSLQ
QNLQTCFHFQ AKEIDIIESP SQFYDLLKTK ILNSQNRIFI ASLYLGKSET
ELVDCISQAL TKNPKLKVSF LLDGLRGTRE LPSACSATLL SSLVAKYGSE
RVDCRLYKTP AYHGWKKVLV PKRFNEGLGL QHMKIYGFDN EVILSGANLS
NDYFTNRQDR YYLFKSRNFS NYYFKLHQLI SSFSYQIIKP MVDGSINIIW
PDSNPTVEPT KNKRLFLREA SQLLDGFLKS SKQSLPITAV GQFSTLVYPI
SQFTPLFPKY NDKSTEKRTI LSLLSTITSN AISWTFTAGY FNILPDIKAK
LLATPVAEAN VITASPFANG FYQSKGVSSN LPGAYLYLSK KFLQDVCRYR
QDHAITLREW QRGVVNKPNG WSYHAKGIWL SARDKNDANN WKPFITVIGS
SNYTRRAYSL DLESNALIIT RDEELRKKMK AELDNLLQYT KPVTLEDFQS
DPERHVGTGV KIATSILGKK L
QNLQTCFHFQ AKEIDIIESP SQFYDLLKTK ILNSQNRIFI ASLYLGKSET
ELVDCISQAL TKNPKLKVSF LLDGLRGTRE LPSACSATLL SSLVAKYGSE
RVDCRLYKTP AYHGWKKVLV PKRFNEGLGL QHMKIYGFDN EVILSGANLS
NDYFTNRQDR YYLFKSRNFS NYYFKLHQLI SSFSYQIIKP MVDGSINIIW
PDSNPTVEPT KNKRLFLREA SQLLDGFLKS SKQSLPITAV GQFSTLVYPI
SQFTPLFPKY NDKSTEKRTI LSLLSTITSN AISWTFTAGY FNILPDIKAK
LLATPVAEAN VITASPFANG FYQSKGVSSN LPGAYLYLSK KFLQDVCRYR
QDHAITLREW QRGVVNKPNG WSYHAKGIWL SARDKNDANN WKPFITVIGS
SNYTRRAYSL DLESNALIIT RDEELRKKMK AELDNLLQYT KPVTLEDFQS
DPERHVGTGV KIATSILGKK L
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
| [159, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
| [159, Phos] | Albuquerque, C.P., Smolka, M.B., Payne, S.H., Bafna, V., Eng, J., Zhou, H. (2008). A multidimensional chromatography technology for in-depth phosphoproteome analysis. Molecular and Cellular Proteomics 7(7):1389-1396. (Publication) (All modifications) |
| [159, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |