Basic Information

NameProtein MSP1 (Tat-binding homolog 4)
Uniprot IDP28737
Systematic gene nameYGR028W
Standard gene nameMSP1
Gene namesMSP1 YTA4 YGR028W
Description from SGDYGR028W MSP1 SGDID:S000003260, Chr VII from 542203-543291, Genome Release 64-3-1, Verified ORF, "Highly-conserved N-terminally anchored AAA-ATPase; distributed in the mitochondrial outer membrane and peroxisomes; involved in mitochondrial protein sorting; functions as an extraction engine in local organelle surveillance to remove and initiate degradation of mistargeted proteins, ensuring fidelity of organelle-specific localization of tail-anchored proteins; contains an N-terminal transmembrane domain and C-terminal cytoplasmic ATPase domain"
Protein length362
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSRKFDLKTI TDLSVLVGTG ISLYYLVSRL LNDVESGPLS GKSRESKAKQ
SLQWEKLVKR SPALAEVTLD AYERTILSSI VTPDEINITF QDIGGLDPLI
SDLHESVIYP LMMPEVYSNS PLLQAPSGVL LYGPPGCGKT MLAKALAKES
GANFISIRMS SIMDKWYGES NKIVDAMFSL ANKLQPCIIF IDEIDSFLRE
RSSTDHEVTA TLKAEFMTLW DGLLNNGRVM IIGATNRIND IDDAFLRRLP
KRFLVSLPGS DQRYKILSVL LKDTKLDEDE FDLQLIADNT KGFSGSDLKE
LCREAALDAA KEYIKQKRQL IDSGTIDVND TSSLKIRPLK TKDFTKKLRM
DATSTLSSQP LD

Legend

  • X Phoshorylation
  • X Ubiquitination

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[40, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[42, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[106, Phos]Papinski, D., Schuschnig, M., Reiter, W., Wilhelm, L., Barnes, C.A., Maiolica, A., Hansmann, I., Pfaffenwimmer, T., Kijanska, M., Stoffel, I., Lee, S.S., Brezovich, A., Lou, J.H., Turk, B.E., Aebersold, R., Ammerer, G., Peter, M., Kraft, C. (2014). Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase. Mol Cell 53: 471-483. (Publication) (All modifications)
[358, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)