Basic Information
Name | Peptide chain release factor 1, mitochondrial (MRF-1) (MtRF-1) |
Uniprot ID | P30775 |
Systematic gene name | YGL143C |
Standard gene name | MRF1 |
Gene names | MRF1 YGL143C |
Description from SGD | YGL143C MRF1 SGDID:S000003111, Chr VII from 235958-234717, Genome Release 64-3-1, reverse complement, Verified ORF, "Mitochondrial translation release factor; involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability" |
Protein length | 413 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MWLSKFQFPS RSIFKGVFLG HKLPLLVRLT STTTNSKSNG SIPTQYTELS
PLLVKQAEKY EAELKDLDKD LSCGIHFDVN KQKHYAKLSA LTDTFIEYKE
KLNELKSLQE MIVSDPSLRA EAEQEYAELV PQYETTSSRL VNKLLPPHPF
ADKPSLLELR PGVGGIEAMI FTQNLLDMYI GYANYRKWKY RIISKNENES
GSGIIDAILS IEEAGSYDRL RFEAGVHRVQ RIPSTETKGR THTSTAAVVV
LPQIGDESAK SIDAYERTFK PGEIRVDIMR ASGKGGQHVN TTDSAVRLTH
IPSGIVVSMQ DERSQHKNKA KAFTILRARL AEKERLEKEE KERKARKSQV
SSTNRSDKIR TYNFPQNRIT DHRCGFTLLD LPGVLSGERL DEVIEAMSKY
DSTERAKELL ESN
PLLVKQAEKY EAELKDLDKD LSCGIHFDVN KQKHYAKLSA LTDTFIEYKE
KLNELKSLQE MIVSDPSLRA EAEQEYAELV PQYETTSSRL VNKLLPPHPF
ADKPSLLELR PGVGGIEAMI FTQNLLDMYI GYANYRKWKY RIISKNENES
GSGIIDAILS IEEAGSYDRL RFEAGVHRVQ RIPSTETKGR THTSTAAVVV
LPQIGDESAK SIDAYERTFK PGEIRVDIMR ASGKGGQHVN TTDSAVRLTH
IPSGIVVSMQ DERSQHKNKA KAFTILRARL AEKERLEKEE KERKARKSQV
SSTNRSDKIR TYNFPQNRIT DHRCGFTLLD LPGVLSGERL DEVIEAMSKY
DSTERAKELL ESN
Legend
- X Phoshorylation
- X Monomethylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[172, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[172, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[179, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[179, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[182, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[182, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[185, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[185, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[287, Mono-CH3] | Polevoda, B., Span, L., Sherman, F. (2006). The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p. J Biol Chem 281: 2562-2571. (Publication) (All modifications) |