P31378

Name	Endonuclease III homolog 1 (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase 1) (DNA glycosylase/AP lyase 1) (Endonuclease III-like glycosylase 1) (Redoxyendonuclease 1)
Uniprot ID	P31378
Systematic gene name	YAL015C
Standard gene name	NTG1
Gene names	NTG1 OGG2 SCR1 YAL015C FUN33
Description from SGD	YAL015C NTG1 SGDID:S000000013, Chr I from 128102-126903, Genome Release 64-3-1, reverse complement, Verified ORF, "DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress; required for maintaining mitochondrial genome integrity; NTG1 has a paralog, NTG2, that arose from the whole genome duplication"
Protein length	399
Download	sequence (fasta, from Uniprot), modifications (csv format)
Database links	Uniprot, SGD, TheCellVision.org, FungiDB

MQKISKYSSM AILRKRPLVK TETGPESELL PEKRTKIKQE EVVPQPVDID
WVKSLPNKQY FEWIVVRNGN VPNRWATPLD PSILVTPAST KVPYKFQETY
ARMRVLRSKI LAPVDIIGGS SIPVTVASKC GISKEQISPR DYRLQVLLGV
MLSSQTKDEV TAMAMLNIMR YCIDELHSEE GMTLEAVLQI NETKLDELIH
SVGFHTRKAK YILSTCKILQ DQFSSDVPAT INELLGLPGV GPKMAYLTLQ
KAWGKIEGIC VDVHVDRLTK LWKWVDAQKC KTPDQTRTQL QNWLPKGLWT
EINGLLVGFG QIITKSRNLG DMLQFLPPDD PRSSLDWDLQ SQLYKEIQQN
IMSYPKWVKY LEGKRELNVE AEINVKHEEK TVEETMVKLE NDISVKVED

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[20, SUMO]	Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[20, SUMO]	Swartzlander, D.B.,  McPherson, A.J.,  Powers, H.R.,  Limpose, K.L.,  Kuiper, E.G.,  Degtyareva, N.P.,  Corbett, A.H., Doetsch, P.W. (2016). Identification of SUMO modification sites in the base excision repair protein, Ntg1. DNA Repair (Amst) 48: 51-62. (Publication) (All modifications)
[23, Phos]	Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[23, Phos]	Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[38, SUMO]	Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[38, SUMO]	Swartzlander, D.B.,  McPherson, A.J.,  Powers, H.R.,  Limpose, K.L.,  Kuiper, E.G.,  Degtyareva, N.P.,  Corbett, A.H., Doetsch, P.W. (2016). Identification of SUMO modification sites in the base excision repair protein, Ntg1. DNA Repair (Amst) 48: 51-62. (Publication) (All modifications)
[341, Phos]	Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[353, Phos]	Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[364, SUMO]	Griffiths, L.M., Swartzlander, D., Meadows, K.L,, Wilkinson, K.D., Corbett, A.H., Doetsch, P.W. (2009). Dynamic compartmentalization of base excision repair proteins in response to nuclear and mitochondrial oxidative stress. Mol Cell Biol 29(3):794-807 (Publication) (All modifications)
[376, SUMO]	Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[376, SUMO]	Swartzlander, D.B.,  McPherson, A.J.,  Powers, H.R.,  Limpose, K.L.,  Kuiper, E.G.,  Degtyareva, N.P.,  Corbett, A.H., Doetsch, P.W. (2016). Identification of SUMO modification sites in the base excision repair protein, Ntg1. DNA Repair (Amst) 48: 51-62. (Publication) (All modifications)
[388, SUMO]	Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications)
[388, SUMO]	Swartzlander, D.B.,  McPherson, A.J.,  Powers, H.R.,  Limpose, K.L.,  Kuiper, E.G.,  Degtyareva, N.P.,  Corbett, A.H., Doetsch, P.W. (2016). Identification of SUMO modification sites in the base excision repair protein, Ntg1. DNA Repair (Amst) 48: 51-62. (Publication) (All modifications)
[396, SUMO]	Swartzlander, D.B.,  McPherson, A.J.,  Powers, H.R.,  Limpose, K.L.,  Kuiper, E.G.,  Degtyareva, N.P.,  Corbett, A.H., Doetsch, P.W. (2016). Identification of SUMO modification sites in the base excision repair protein, Ntg1. DNA Repair (Amst) 48: 51-62. (Publication) (All modifications)