Basic Information
Name | Mitochondrial glycine transporter YMC1 |
Uniprot ID | P32331 |
Systematic gene name | YPR058W |
Standard gene name | YMC1 |
Gene names | YMC1 YPR058W YP9499.14 |
Description from SGD | YPR058W YMC1 SGDID:S000006262, Chr XVI from 673751-674674, Genome Release 64-3-1, Verified ORF, "Secondary mitochondrial inner membrane glycine transporter; required with HEM25 for the transport of glycine into mitochondria for the initiation of heme biosynthesis; proposed role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; localizes to the vacuole in response to H2O2; YMC1 has a paralog, YMC2, that arose from the whole genome duplication" |
Protein length | 307 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MSEEFPSPQL IDDLEEHPQH DNARVVKDLL AGTAGGIAQV LVGQPFDTTK
VRLQTSSTPT TAMEVVRKLL ANEGPRGFYK GTLTPLIGVG ACVSLQFGVN
EAMKRFFHHR NADMSSTLSL PQYYACGVTG GIVNSFLASP IEHVRIRLQT
QTGSGTNAEF KGPLECIKKL RHNKALLRGL TPTILREGHG CGTYFLVYEA
LIANQMNKRR GLERKDIPAW KLCIFGALSG TALWLMVYPL DVIKSVMQTD
NLQKPKFGNS ISSVAKTLYA NGGIGAFFKG FGPTMLRAAP ANGATFATFE
LAMRLLG
VRLQTSSTPT TAMEVVRKLL ANEGPRGFYK GTLTPLIGVG ACVSLQFGVN
EAMKRFFHHR NADMSSTLSL PQYYACGVTG GIVNSFLASP IEHVRIRLQT
QTGSGTNAEF KGPLECIKKL RHNKALLRGL TPTILREGHG CGTYFLVYEA
LIANQMNKRR GLERKDIPAW KLCIFGALSG TALWLMVYPL DVIKSVMQTD
NLQKPKFGNS ISSVAKTLYA NGGIGAFFKG FGPTMLRAAP ANGATFATFE
LAMRLLG
Legend
- X SUMOylation
- X K-Succinylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[68, SUMO] | Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications) |
[254, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |