Basic Information
| Name | Probable folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase) |
| Uniprot ID | P36001 |
| Systematic gene name | YKL132C |
| Standard gene name | RMA1 |
| Gene names | RMA1 YKL132C |
| Description from SGD | YKL132C RMA1 SGDID:S000001615, Chr XI from 194866-193574, Genome Release 64-3-1, reverse complement, Verified ORF, "Putative dihydrofolate synthetase; similar to E. coli folylpolyglutamate synthetase/dihydrofolate synthetase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; RMA1 has a paralog, FOL3, that arose from the whole genome duplication" |
| Protein length | 430 |
| Download | sequence (fasta, from Uniprot), modifications (csv format) |
| Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MDDISGRQTL PRINRLLEHV GNPQDSLSIL HIAGTNGKET VSKFLTSILQ
HPGQQRQRVL IGRYTTSSLL NAKEEDISIN NEAISLIEYS RIEKELIEAD
SSLKLQCNNL ELLTSVALVY FAKKNCQWCI IETGLAGKQD PGSIIAGQSR
VCCAITNVGI SDEAFLCKFL SQITESSTNK AIFLLDGSND EFVRNTITKR
CHDVGCPLEI TDPSLRDYNV HTDTWGTLEV RLPYSEEEYQ IFNLRVAIAV
LDFLSKEKKV CISKDQLSQG LISVDWPRSL HRLDYCYEST SGKKIALLLD
NANNAKAARN LACHLRTTYG DTPLTFVIAI TTGKKVSPLL DPLIRPQDYV
IVTRFGSVVG MPWIQSLEPV NLLAFIKNRY TRNVNMQPDL QSVWTFLETS
GLKTIVPVIV CGSLYICKEL LRLHNCHLPV
HPGQQRQRVL IGRYTTSSLL NAKEEDISIN NEAISLIEYS RIEKELIEAD
SSLKLQCNNL ELLTSVALVY FAKKNCQWCI IETGLAGKQD PGSIIAGQSR
VCCAITNVGI SDEAFLCKFL SQITESSTNK AIFLLDGSND EFVRNTITKR
CHDVGCPLEI TDPSLRDYNV HTDTWGTLEV RLPYSEEEYQ IFNLRVAIAV
LDFLSKEKKV CISKDQLSQG LISVDWPRSL HRLDYCYEST SGKKIALLLD
NANNAKAARN LACHLRTTYG DTPLTFVIAI TTGKKVSPLL DPLIRPQDYV
IVTRFGSVVG MPWIQSLEPV NLLAFIKNRY TRNVNMQPDL QSVWTFLETS
GLKTIVPVIV CGSLYICKEL LRLHNCHLPV
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
| [149, Phos] | Pultz, D., Bennetzen, M.V., Rødkær, S.V., Zimmermann, C., Enserink, J.M., Andersen, J.S., Færgeman, N.J. (2012). Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae. Mol Biosyst 8: 796-803. (Publication) (All modifications) |