Basic Information
Name | CCR4-associated factor 4 |
Uniprot ID | P36130 |
Systematic gene name | YKR036C |
Standard gene name | CAF4 |
Gene names | CAF4 YKR036C |
Description from SGD | YKR036C CAF4 SGDID:S000001744, Chr XI from 510633-508702, Genome Release 64-3-1, reverse complement, Verified ORF, "WD40 repeat-containing protein associated with the CCR4-NOT complex; interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission; CAF4 has a paralog, MDV1, that arose from the whole genome duplication" |
Protein length | 643 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MGSGDTRGES SLVAKPIEII LNKLPHAILA QQQFQKYITS PIYRYLSKLL
LFREVAWPES TKDTQKGQVG IFSFQNNYAD SATTFRILAH LDEQRYPLPN
GAAEKNLPSL FEGFKATVSI IQQRLLLDNV DGATNSDKEK YVQLPDINTG
FVNKTYSRID LTHLLEDVET NVENLSINKT LEMDELTRLD SMINELESRK
LKILERVKHI DSKSTNLEND VTLIKDRINF IEEYNLEADR EQSLRKQMEE
ERSSEASSFT QNEEAISSLC DVESKDTRLK DFYKMPHEKS HDKNRQIISE
TYSRNTTAFR MTIPHGEHGN SITALDFDTP WGTLCSSSYQ DRIVKVWDLN
HGIQVGELPG HLATVNCMQI DKKNYNMLIT GSKDATLKLW DLNLSREIYL
DHSPLKEKTE EIVTPCIHNF ELHKDEITAL SFDSEALVSG SRDKKIFHWD
LTTGKCIQQL DLIFTPTHSD IKMPARSLNN GACLLGTEAP MIGALQCYNS
ALATGTKDGI VRLWDLRVGK PVRLLEGHTD GITSLKFDSE KLVTGSMDNS
VRIWDLRTSS ILDVIAYDLP VSSLDFDGKL ITVGANEGGV NVFNMERDEH
WMTPEPPHSL DGDELSRRIA IVKYKDGFLI NGHNDGDINV WTL
LFREVAWPES TKDTQKGQVG IFSFQNNYAD SATTFRILAH LDEQRYPLPN
GAAEKNLPSL FEGFKATVSI IQQRLLLDNV DGATNSDKEK YVQLPDINTG
FVNKTYSRID LTHLLEDVET NVENLSINKT LEMDELTRLD SMINELESRK
LKILERVKHI DSKSTNLEND VTLIKDRINF IEEYNLEADR EQSLRKQMEE
ERSSEASSFT QNEEAISSLC DVESKDTRLK DFYKMPHEKS HDKNRQIISE
TYSRNTTAFR MTIPHGEHGN SITALDFDTP WGTLCSSSYQ DRIVKVWDLN
HGIQVGELPG HLATVNCMQI DKKNYNMLIT GSKDATLKLW DLNLSREIYL
DHSPLKEKTE EIVTPCIHNF ELHKDEITAL SFDSEALVSG SRDKKIFHWD
LTTGKCIQQL DLIFTPTHSD IKMPARSLNN GACLLGTEAP MIGALQCYNS
ALATGTKDGI VRLWDLRVGK PVRLLEGHTD GITSLKFDSE KLVTGSMDNS
VRIWDLRTSS ILDVIAYDLP VSSLDFDGKL ITVGANEGGV NVFNMERDEH
WMTPEPPHSL DGDELSRRIA IVKYKDGFLI NGHNDGDINV WTL
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[39, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[40, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[134, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[136, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[136, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[136, Phos] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[136, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[191, Phos] | Zhou, X., Li, W., Liu, Y., Amon, A. (2021. Cross-compartment signal propagation in the mitotic exit network. Elife 10:e63645. (Publication) (All modifications) |
[243, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[260, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[260, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
[290, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[403, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[403, Phos] | Renvoisé M, Bonhomme L, Davanture M, et al (2014) Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae. Journal of Proteomics 106:140–150. (Publication) (All modifications) |
[403, Phos] | Guo X, Niemi NM, Coon JJ, Pagliarini DJ (2017a) Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase. J Biol Chem 292:11751–11759. (Publication) (All modifications) |
[403, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[403, Phos] | Zhou, X., Li, W., Liu, Y., Amon, A. (2021. Cross-compartment signal propagation in the mitotic exit network. Elife 10:e63645. (Publication) (All modifications) |
[403, Phos] | MacGilvray, M.E., Shishkova, E., Place, M., Wagner, E.R., Coon, J.J., Gasch, A.P. (2020). Phosphoproteome response to dithiothreitol reveals unique versus shared features of Saccharomyces cerevisiae stress responses. Journal of Proteome Research 19(8): 3405-3417. (Publication) (All modifications) |
[403, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |