Basic Information

NameProbable secreted beta-glucosidase UTH1 (EC 3.2.1.-) (Youth protein 1)
Uniprot IDP36135
Systematic gene nameYKR042W
Standard gene nameUTH1
Gene namesUTH1 YKR042W
Description from SGDYKR042W UTH1 SGDID:S000001750, Chr XI from 519527-520624, Genome Release 64-3-1, Verified ORF, "Mitochondrial inner membrane protein; role in mitophagy is disputed; implicated in cell wall biogenesis, the oxidative stress response, life span during starvation, and cell death; SUN family member; UTH1 has a paralog, NCA3, that arose from the whole genome duplication"
Protein length365
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MKLSALLALS ASTAVLAAPA VHHSDNHHHN DKRAVVTVTQ YVNADGAVVI
PAATTATSAA ADGKVESVAA ATTTLSSTAA AATTSAAASS SSSSSSSSSS
SSSVGSGDFE DGTISCSDFP SGQGAVSLDW LGLGGWASIM DMNGNTATSC
QDGYYCSYAC SPGYAKTQWP SEQPSDGRSV GGLYCKNGKL YRSNTDTNSL
CVEGQGSAQA VNKVSGSIAI CGTDYPGSEN MVVPTVVGAG SSQPINVIKE
DSYYQWQGKK TSAQYYVNNA GVSVEDGCIW GTEGSGVGNW APVVLGAGYT
DGITYLSIIP NPNNKEAPNF NIKIVATDGS TVNGACSYEN GVYSGSGSDG
CTVSVTSGSA NFVFY

Legend

  • X K-acetylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[186, K-acetyl]Henriksen, P., Wagner, S. A., Weinert, B. T., et al. (2012). Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Molecular & Cellular Proteomics, 11(11), 1510-1522. (Publication) (All modifications)