Basic Information
| Name | 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Extracellular matrix protein 31) (Ketopantoate hydroxymethyltransferase) |
| Uniprot ID | P38122 |
| Systematic gene name | YBR176W |
| Standard gene name | ECM31 |
| Gene names | ECM31 YBR176W YBR1238 |
| Description from SGD | YBR176W ECM31 SGDID:S000000380, Chr II from 583720-584658, Genome Release 64-3-1, Verified ORF, "Ketopantoate hydroxymethyltransferase; required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate" |
| Protein length | 312 |
| Download | sequence (fasta, from Uniprot), modifications (csv format) |
| Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MNIMKRQLCT SSKRFFSTAK NVVKYNTIQD IRNKYFTGTP LSMCTAYDFI
TATWVNKANC DLLLVGDSLA MTSLGYDSTI TLSLNEFKYH VASVCRAEGS
SMVVVDMPFG TFESGISDGL KNAIDIMKLD SKVTSVKVEV GSYTKDKYAM
KFIEELCSRG IPVMAHIGLT PQKVHSLGGY KVQGSKSLLQ MQELYETAMQ
LQKIGCWSIL IECVPHKMAQ FITSKLSVPT IGIGAGNGTS GQVLVISDLL
GMQGDSVPKF VKQAVNMTDI ATQGLKEYIA SVEDRTFPER GTHTFKVKED
LWNEFLSSIN EK
TATWVNKANC DLLLVGDSLA MTSLGYDSTI TLSLNEFKYH VASVCRAEGS
SMVVVDMPFG TFESGISDGL KNAIDIMKLD SKVTSVKVEV GSYTKDKYAM
KFIEELCSRG IPVMAHIGLT PQKVHSLGGY KVQGSKSLLQ MQELYETAMQ
LQKIGCWSIL IECVPHKMAQ FITSKLSVPT IGIGAGNGTS GQVLVISDLL
GMQGDSVPKF VKQAVNMTDI ATQGLKEYIA SVEDRTFPER GTHTFKVKED
LWNEFLSSIN EK
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
Use imported representation
Loading structure from server... It may take a while.
If you believe something went wrong, please make sure PDB ID is correct.
Please also make sure that WebGL is enabled in your browser.
- Internet Explorer: sorry. IE doesn't support WebGL.
- Firefox (version 4 or later): try force enable WebGL.
- Chrome: try force enable WebGL.
- Safari: enable WebGL.
References
| [292, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
| [292, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |