Basic Information

NameInner membrane mitoribosome receptor MBA1, mitochondrial (Multi-copy bypass of AFG3 protein)
Uniprot IDP38300
Systematic gene nameYBR185C
Standard gene nameMBA1
Gene namesMBA1 YBR185C YBR1307
Description from SGDYBR185C MBA1 SGDID:S000000389, Chr II from 599959-599123, Genome Release 64-3-1, reverse complement, Verified ORF, "Membrane-associated mitoribosome receptor; involved along with Dpi29p in the cotranslational insertion of nascent polypeptide chains into the inner mitochondrial membrane; associates with nascent polypeptide chains; interacts with Mdm38p and may recruit mRNA-specific translational activators to the mitoribosome; null mutant displays decreased tolerance to mistranslation-induced proteotoxic stress; localizes to the inner mitochondrial membrane"
Protein length278
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSVLRSTCLF FPPRSLLISF NKRRLFSTSR LILNKESETT KKKDKSKQQD
FNPRHLGVAA EIFIPSAYKN LPNVFAHPLI VANALIRRLY TFGLNSVQVA
LFRFQSGIKP SFLLWKNKAI ETYINVNTSF AHKNLSDIKG LVSLWVQEAL
EARSRQLPGN ATLDWQLIKF NAVPKLVSVQ PIMIPGMPLE HLQLVYKFDT
KQRLIKVNQQ TKKTETLDRD VVDYIAFLCD ATTNDMILMG SLFESKPNDK
LPKSYEDDAK VAIHRMKVNG DIYRLPPS

Legend

  • X K-Succinylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[206, K-succ]Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)
[260, K-succ]Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)