P38342

Name	3-ketodihydrosphingosine reductase TSC10 (EC 1.1.1.102) (3-dehydrosphinganine reductase) (KDS reductase) (Temperature-sensitive CSG2 suppressor protein 10)
Uniprot ID	P38342
Systematic gene name	YBR265W
Standard gene name	TSC10
Gene names	TSC10 YBR265W YBR1734
Description from SGD	YBR265W TSC10 SGDID:S000000469, Chr II from 738582-739544, Genome Release 64-3-1, Verified ORF, "3-ketosphinganine reductase; catalyzes the second step in phytosphingosine synthesis; essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine; localized to lipid droplets; member of short chain dehydrogenase/reductase protein family; mutations in human homolog KDSR cause recessive progressive symmetric erythrokeratoderma"
Protein length	320
Download	sequence (fasta, from Uniprot), modifications (csv format)
Database links	Uniprot, SGD, TheCellVision.org, FungiDB

MKFTLEDQVV LITGGSQGLG KEFAKKYYNE AENTKIIIVS RSEARLLDTC
NEIRIEAHLR RETTDEGQVQ HKLAAPLDLE QRLFYYPCDL SCYESVECLF
NALRDLDLLP TQTLCCAGGA VPKLFRGLSG HELNLGMDIN YKTTLNVAHQ
IALAEQTKEH HLIIFSSATA LYPFVGYSQY APAKAAIKSL VAILRQELTN
FRISCVYPGN FESEGFTVEQ LTKPEITKLI EGPSDAIPCK QACDIIAKSL
ARGDDDVFTD FVGWMIMGMD LGLTAKKSRF VPLQWIFGVL SNILVVPFYM
VGCSWYIRKW FRENDGKKAN

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[63, Phos]	Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[63, Phos]	Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[64, Phos]	Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[64, Phos]	Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[72, Ubi]	Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[223, Ubi]	Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[240, Ubi]	Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)