Basic Information
| Name | Exopolyphosphatase (ExopolyPase) (EC 3.6.1.11) (Metaphosphatase) |
| Uniprot ID | P38698 |
| Systematic gene name | YHR201C |
| Standard gene name | PPX1 |
| Gene names | PPX1 YHR201C |
| Description from SGD | YHR201C PPX1 SGDID:S000001244, Chr VIII from 501143-499950, Genome Release 64-3-1, reverse complement, Verified ORF, "Exopolyphosphatase; hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix" |
| Protein length | 397 |
| Download | sequence (fasta, from Uniprot), modifications (csv format) |
| Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MSPLRKTVPE FLAHLKSLPI SKIASNDVLT ICVGNESADM DSIASAITYS
YCQYIYNEGT YSEEKKKGSF IVPIIDIPRE DLSLRRDVMY VLEKLKIKEE
ELFFIEDLKS LKQNVSQGTE LNSYLVDNND TPKNLKNYID NVVGIIDHHF
DLQKHLDAEP RIVKVSGSCS SLVFNYWYEK LQGDREVVMN IAPLLMGAIL
IDTSNMRRKV EESDKLAIER CQAVLSGAVN EVSAQGLEDS SEFYKEIKSR
KNDIKGFSVS DILKKDYKQF NFQGKGHKGL EIGLSSIVKR MSWLFNEHGG
EADFVNQCRR FQAERGLDVL VLLTSWRKAG DSHRELVILG DSNVVRELIE
RVSDKLQLQL FGGNLDGGVA MFKQLNVEAT RKQVVPYLEE AYSNLEE
YCQYIYNEGT YSEEKKKGSF IVPIIDIPRE DLSLRRDVMY VLEKLKIKEE
ELFFIEDLKS LKQNVSQGTE LNSYLVDNND TPKNLKNYID NVVGIIDHHF
DLQKHLDAEP RIVKVSGSCS SLVFNYWYEK LQGDREVVMN IAPLLMGAIL
IDTSNMRRKV EESDKLAIER CQAVLSGAVN EVSAQGLEDS SEFYKEIKSR
KNDIKGFSVS DILKKDYKQF NFQGKGHKGL EIGLSSIVKR MSWLFNEHGG
EADFVNQCRR FQAERGLDVL VLLTSWRKAG DSHRELVILG DSNVVRELIE
RVSDKLQLQL FGGNLDGGVA MFKQLNVEAT RKQVVPYLEE AYSNLEE
Legend
- X SUMOylation
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
| [6, SUMO] | Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications) |
| [25, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
| [393, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |