Basic Information
Name | Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) |
Uniprot ID | P38816 |
Systematic gene name | YHR106W |
Standard gene name | TRR2 |
Gene names | TRR2 YHR106W |
Description from SGD | YHR106W TRR2 SGDID:S000001148, Chr VIII from 325598-326626, Genome Release 64-3-1, Verified ORF, "Mitochondrial thioredoxin reductase; involved in protection against oxidative stress, required with Glr1p to maintain the redox state of Trx3p; contains active-site motif (CAVC) present in prokaryotic orthologs; binds NADPH and FAD; TRR2 has a paralog, TRR1, that arose from the whole genome duplication" |
Protein length | 342 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MIKHIVSPFR TNFVGISKSV LSRMIHHKVT IIGSGPAAHT AAIYLARAEM
KPTLYEGMMA NGIAAGGQLT TTTDIENFPG FPESLSGSEL MERMRKQSAK
FGTNIITETV SKVDLSSKPF RLWTEFNEDA EPVTTDAIIL ATGASAKRMH
LPGEETYWQQ GISACAVCDG AVPIFRNKPL AVIGGGDSAC EEAEFLTKYA
SKVYILVRKD HFRASVIMQR RIEKNPNIIV LFNTVALEAK GDGKLLNMLR
IKNTKSNVEN DLEVNGLFYA IGHSPATDIV KGQVDEEETG YIKTVPGSSL
TSVPGFFAAG DVQDSRYRQA VTSAGSGCIA ALDAERYLSA QE
KPTLYEGMMA NGIAAGGQLT TTTDIENFPG FPESLSGSEL MERMRKQSAK
FGTNIITETV SKVDLSSKPF RLWTEFNEDA EPVTTDAIIL ATGASAKRMH
LPGEETYWQQ GISACAVCDG AVPIFRNKPL AVIGGGDSAC EEAEFLTKYA
SKVYILVRKD HFRASVIMQR RIEKNPNIIV LFNTVALEAK GDGKLLNMLR
IKNTKSNVEN DLEVNGLFYA IGHSPATDIV KGQVDEEETG YIKTVPGSSL
TSVPGFFAAG DVQDSRYRQA VTSAGSGCIA ALDAERYLSA QE
Legend
- X SUMOylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[202, SUMO] | Bhagwat, N.R., Owens, S.N., Ito, M., Boinapalli, J.V,, Poa, P., Ditzel, A., Kopparapu, S., Mahalawat, M., Davies, O.R., Collins, S.R., Johnson, J.R., Krogan, N.J., Hunter, N. (2021). SUMO is a pervasive regulator of meiosis. Elife 10:e57720. (Publication) (All modifications) |