Basic Information
| Name | Aspartyl aminopeptidase 4 (EC 3.4.11.21) |
| Uniprot ID | P38821 |
| Systematic gene name | YHR113W |
| Standard gene name | APE4 |
| Gene names | APE4 YHR113W |
| Description from SGD | YHR113W APE4 SGDID:S000001155, Chr VIII from 336337-337809, Genome Release 64-3-1, Verified ORF, "Cytoplasmic aspartyl aminopeptidase with possible vacuole function; Cvt pathway cargo protein; cleaves unblocked N-terminal acidic amino acids from peptide substrates; forms a 12-subunit homo-oligomer; M18 metalloprotease family" |
| Protein length | 490 |
| Download | sequence (fasta, from Uniprot), modifications (csv format) |
| Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MFRIQLRTMS SKTCKSDYPK EFVSFLNSSH SPYHTVHNIK KHLVSNGFKE
LSERDSWAGH VAQKGKYFVT RNGSSIIAFA VGGKWEPGNP IAITGAHTDS
PALRIKPISK RVSEKYLQVG VETYGGAIWH SWFDKDLGVA GRVFVKDAKT
GKSIARLVDL NRPLLKIPTL AIHLDRDVNQ KFEFNRETQL LPIGGLQEDK
TEAKTEKEIN NGEFTSIKTI VQRHHAELLG LIAKELAIDT IEDIEDFELI
LYDHNASTLG GFNDEFVFSG RLDNLTSCFT SMHGLTLAAD TEIDRESGIR
LMACFDHEEI GSSSAQGADS NFLPNILERL SILKGDGSDQ TKPLFHSAIL
ETSAKSFFLS SDVAHAVHPN YANKYESQHK PLLGGGPVIK INANQRYMTN
SPGLVLVKRL AEAAKVPLQL FVVANDSPCG STIGPILASK TGIRTLDLGN
PVLSMHSIRE TGGSADLEFQ IKLFKEFFER YTSIESEIVV
LSERDSWAGH VAQKGKYFVT RNGSSIIAFA VGGKWEPGNP IAITGAHTDS
PALRIKPISK RVSEKYLQVG VETYGGAIWH SWFDKDLGVA GRVFVKDAKT
GKSIARLVDL NRPLLKIPTL AIHLDRDVNQ KFEFNRETQL LPIGGLQEDK
TEAKTEKEIN NGEFTSIKTI VQRHHAELLG LIAKELAIDT IEDIEDFELI
LYDHNASTLG GFNDEFVFSG RLDNLTSCFT SMHGLTLAAD TEIDRESGIR
LMACFDHEEI GSSSAQGADS NFLPNILERL SILKGDGSDQ TKPLFHSAIL
ETSAKSFFLS SDVAHAVHPN YANKYESQHK PLLGGGPVIK INANQRYMTN
SPGLVLVKRL AEAAKVPLQL FVVANDSPCG STIGPILASK TGIRTLDLGN
PVLSMHSIRE TGGSADLEFQ IKLFKEFFER YTSIESEIVV
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
| [75, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
| [75, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
| [109, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
| [109, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
| [150, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
| [150, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |
| [401, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |