Basic Information

NamePentamidine resistance factor, mitochondrial
Uniprot IDP38969
Systematic gene nameYOR266W
Standard gene namePNT1
Gene namesPNT1 YOR266W
Description from SGDYOR266W PNT1 SGDID:S000005792, Chr XV from 821023-822294, Genome Release 64-3-1, Verified ORF, "Mitochondrial integral inner membrane protein; involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p; deletion mutant sensitive to the anti-Pneumocystis carinii drug pentamidine"
Protein length423
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MDSRVALVRK YIAPSVIKSD SIQLHGLVKA PLFKALNSRY KLGSLQIVQD
VDWNAKTTPS DSPEPLAATL NSNRSLPMTK FPKQEILEQV KLDTKVGKWR
KFMTGWFRIG LYLLKSYKTG IQNTLKVFWD TRNEEQKFSI KNGALANLVR
EIEMHEINTR LSSSSLPTSS SAKAPLRPLS INRKTLVELI RRDQIWKLPV
FFTLVFIFEE VSVLIFTFFP RVCPYNCLTP GGYKKLSNSY IKGTTSTQGN
YGLGPLEFTK QGTIKYEPPY AVPIENLYNF LTSFPQSMIS NWKLYIYKKL
KLQKLLCNEI EKIYQYLFID DWLLLQSILN TDVEKTKIAL SDRELVNCIL
ERKLYHMGDD LNEMVNDTLG KEILLKRLFL YWTLRYNDTI SLNGKHTFSE
KWGVNNISLL KYNSELVATK DIQ

Legend

  • X Phoshorylation
  • X K-Succinylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[11, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[11, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[15, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[15, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[29, K-succ]Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)
[34, K-succ]Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications)
[246, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[246, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[251, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[251, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[414, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)