Basic Information
| Name | BolA-like protein 3 (Altered inheritance of mitochondria protein 1) |
| Uniprot ID | P39724 |
| Systematic gene name | YAL046C |
| Standard gene name | BOL3 |
| Gene names | BOL3 AIM1 YAL046C |
| Description from SGD | YAL046C BOL3 SGDID:S000000044, Chr I from 57385-57029, Genome Release 64-3-1, reverse complement, Verified ORF, "Protein involved in Fe-S cluster transfer to mitochondrial clients; protects [4Fe-4S] clusters from damage due to oxidative stress by acting along with Nfu1p at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to mitochondrial client proteins like lipoate synthase and succinate dehydrogenase; sequence similarity to human BOLA family member, BOLA3, mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome (MMDS2)" |
| Protein length | 118 |
| Download | sequence (fasta, from Uniprot), modifications (csv format) |
| Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MKLPQTMLRS ISVKHVRWPR ILTGSKLWYS TQMAMTPEEK MITDKLQQEL
EPEVCKVQDV SGGCGSMFAI NITSKKFNGL SLIKQHQLVN RILRDDISRW
HGLQLTTKKS TGKGPASS
EPEVCKVQDV SGGCGSMFAI NITSKKFNGL SLIKQHQLVN RILRDDISRW
HGLQLTTKKS TGKGPASS
Legend
- X K-Succinylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
| [108, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |