Basic Information
Name | Plasma membrane iron permease |
Uniprot ID | P40088 |
Systematic gene name | YER145C |
Standard gene name | FTR1 |
Gene names | FTR1 YER145C |
Description from SGD | YER145C FTR1 SGDID:S000000947, Chr V from 461740-460526, Genome Release 64-3-1, reverse complement, Verified ORF, "High affinity iron permease; involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron; protein abundance increases in response to DNA replication stress" |
Protein length | 404 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MPNKVFNVAV FFVVFRECLE AVIVISVLLS FLKQAIGEHD RALYRKLRIQ
VWVGVLLGFI ICLAIGAGFI GAYYSLQKDI FGSAEDLWEG IFCMIATIMI
SMMGIPMLRM NKMQSKWRVK IARSLVEIPH RKRDYFKIGF LSRRYAMFLL
PFITVLREGL EAVVFVAGAG ITTQGSHASA YPLPVVVGLI CGGLVGYLLY
YGASKSSLQI FLILSTSILY LISAGLFSRG AWYFENYRFN LASGGDASEG
GDGNGSYNIR KAVYHVNCCN PELDNGWDIF NALLGWQNTG YLSSMLCYNI
YWLVLIIVLS LMIFEERRGH LPFTKNLQLK HLNPGYWIKN KKKQELTEEQ
KRQLFAKMEN INFNEDGEIN VQENYELPEQ TTSHSSSQNV ATDKEVLHVK
ADSL
VWVGVLLGFI ICLAIGAGFI GAYYSLQKDI FGSAEDLWEG IFCMIATIMI
SMMGIPMLRM NKMQSKWRVK IARSLVEIPH RKRDYFKIGF LSRRYAMFLL
PFITVLREGL EAVVFVAGAG ITTQGSHASA YPLPVVVGLI CGGLVGYLLY
YGASKSSLQI FLILSTSILY LISAGLFSRG AWYFENYRFN LASGGDASEG
GDGNGSYNIR KAVYHVNCCN PELDNGWDIF NALLGWQNTG YLSSMLCYNI
YWLVLIIVLS LMIFEERRGH LPFTKNLQLK HLNPGYWIKN KKKQELTEEQ
KRQLFAKMEN INFNEDGEIN VQENYELPEQ TTSHSSSQNV ATDKEVLHVK
ADSL
Legend
- X Ubiquitination
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[351, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[400, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[403, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[403, Phos] | MacGilvray, M.E., Shishkova, E., Place, M., Wagner, E.R., Coon, J.J., Gasch, A.P. (2020). Phosphoproteome response to dithiothreitol reveals unique versus shared features of Saccharomyces cerevisiae stress responses. Journal of Proteome Research 19(8): 3405-3417. (Publication) (All modifications) |
[403, Phos] | Holt, L.J., Tuch, B.B., Villén, J., Johnson, A.D., Gygi, S.P., Morgan, D.O. (2009). Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 325(5948): 1682-1686. (Publication) (All modifications) |
[403, Phos] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |