Basic Information
Name | Mitochondrial respiratory chain complexes assembly protein YTA12 (EC 3.4.24.-) (Tat-binding homolog 12) |
Uniprot ID | P40341 |
Systematic gene name | YMR089C |
Standard gene name | YTA12 |
Gene names | YTA12 RCA1 YMR089C YM9582.14C |
Description from SGD | YMR089C YTA12 SGDID:S000004695, Chr XIII from 448086-445609, Genome Release 64-3-1, reverse complement, Verified ORF, "Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; overexpression of human AFG3L2 complements respiratory defect of yeast afg3 yta12 double null mutation, but overexpression of disease-associated AFG3L2 variants does not; expression of both human SPG7 (paraplegin) and AFG3L2 complements yeast yta12 afg3 double mutation" |
Protein length | 825 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MLLLSWSRIA TKVVRRPVRF RSYYGLTHIK SLHTQYRLLN RLQENKSGNK
NEDNNEDAKL NKEIPTDEEV EAIRKQVEKY IEQTKNNTIP ANWKEQKRKI
DESIRRLEDA VLKQESNRIQ EERKEKEEEN GPSKAKSNRT KEQGYFEGNN
SRNIPPPPPP PPPKPPLNDP SNPVSKNVNL FQIGLTFFLL SFLLDLLNSL
EEQSEITWQD FREKLLAKGY VAKLIVVNKS MVKVMLNDNG KNQADNYGRN
FYYFTIGSID SFEHKLQKAQ DELDIDKDFR IPVLYVQEGN WAKAMFQILP
TVLMIAGIIW LTRRSAQAAG GSRGGIFGLS RSKAKKFNTE TDVKIKFKDV
AGCDEAKEEI MEFVSFLKEP SRYEKMGAKI PRGAILSGPP GTGKTLLAKA
TAGEAGVPFY FVSGSEFVEM FVGVGAARVR DLFKTARENA PSIVFIDEID
AIGKARQKGN FSGANDEREN TLNQMLVEMD GFTPADHVVV LAGTNRPDIL
DKALLRPGRF DRHINIDKPE LEGRKAIFAV HLHHLKLAGE IFDLKNRLAA
LTPGFSGADI ANVCNEAALI AARSDEDAVK LNHFEQAIER VIGGVERKSK
LLSPEEKKVV AYHEAGHAVC GWYLKYADPL LKVSIIPRGQ GALGYAQYLP
GDIFLLTEQQ LKDRMTMSLG GRVSEELHFP SVTSGASDDF KKVTSMATAM
VTELGMSDKI GWVNYQKRDD SDLTKPFSDE TGDIIDSEVY RIVQECHDRC
TKLLKEKAED VEKIAQVLLK KEVLTREDMI DLLGKRPFPE RNDAFDKYLN
DYETEKIRKE EEKNEKRNEP KPSTN
NEDNNEDAKL NKEIPTDEEV EAIRKQVEKY IEQTKNNTIP ANWKEQKRKI
DESIRRLEDA VLKQESNRIQ EERKEKEEEN GPSKAKSNRT KEQGYFEGNN
SRNIPPPPPP PPPKPPLNDP SNPVSKNVNL FQIGLTFFLL SFLLDLLNSL
EEQSEITWQD FREKLLAKGY VAKLIVVNKS MVKVMLNDNG KNQADNYGRN
FYYFTIGSID SFEHKLQKAQ DELDIDKDFR IPVLYVQEGN WAKAMFQILP
TVLMIAGIIW LTRRSAQAAG GSRGGIFGLS RSKAKKFNTE TDVKIKFKDV
AGCDEAKEEI MEFVSFLKEP SRYEKMGAKI PRGAILSGPP GTGKTLLAKA
TAGEAGVPFY FVSGSEFVEM FVGVGAARVR DLFKTARENA PSIVFIDEID
AIGKARQKGN FSGANDEREN TLNQMLVEMD GFTPADHVVV LAGTNRPDIL
DKALLRPGRF DRHINIDKPE LEGRKAIFAV HLHHLKLAGE IFDLKNRLAA
LTPGFSGADI ANVCNEAALI AARSDEDAVK LNHFEQAIER VIGGVERKSK
LLSPEEKKVV AYHEAGHAVC GWYLKYADPL LKVSIIPRGQ GALGYAQYLP
GDIFLLTEQQ LKDRMTMSLG GRVSEELHFP SVTSGASDDF KKVTSMATAM
VTELGMSDKI GWVNYQKRDD SDLTKPFSDE TGDIIDSEVY RIVQECHDRC
TKLLKEKAED VEKIAQVLLK KEVLTREDMI DLLGKRPFPE RNDAFDKYLN
DYETEKIRKE EEKNEKRNEP KPSTN
Legend
- X K-Succinylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[79, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |
[141, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |
[336, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |
[545, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |
[632, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |
[770, K-succ] | Frankovsky, J., Keresztesová, B., Bellová, J., et al. (2021). The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids. Journal of Biological Chemistry, 297(4): 101155. (Publication) (All modifications) |