Basic Information

Name5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.99.60) (Catabolite repression protein 5) (Ubiquinone biosynthesis monooxygenase COQ7)
Uniprot IDP41735
Systematic gene nameYOR125C
Standard gene nameCAT5
Gene namesCAT5 COQ7 YOR125C O3284 YOR3284C
Description from SGDYOR125C CAT5 SGDID:S000005651, Chr XV from 559731-559030, Genome Release 64-3-1, reverse complement, Verified ORF, "Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation"
Protein length233
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MLSRVSVFKP ASRGFSVLSS LKITEHTSAK HTEKPEHAPK CQNLSDAQAA
FLDRVIRVDQ AGELGADYIY AGQYFVLAHR YPHLKPVLKH IWDQEIHHHN
TFNNLQLKRR VRPSLLTPLW KAGAFAMGAG TALISPEAAM ACTEAVETVI
GGHYNGQLRN LANQFNLERT DGTKGPSEEI KSLTSTIQQF RDDELEHLDT
AIKHDSYMAV PYTVITEGIK TICRVAIWSA ERI

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[20, Phos]Martín-Montalvo, A., González-Mariscal, I., Padilla, S., Ballesteros, M., Brautigan, D.L., Navas, P., Santos-Ocaña, C. (2011). Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p. Biochem J 440: 107-114. (Publication) (All modifications)
[28, Phos]Martín-Montalvo, A., González-Mariscal, I., Padilla, S., Ballesteros, M., Brautigan, D.L., Navas, P., Santos-Ocaña, C. (2011). Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p. Biochem J 440: 107-114. (Publication) (All modifications)
[32, Phos]Martín-Montalvo, A., González-Mariscal, I., Padilla, S., Ballesteros, M., Brautigan, D.L., Navas, P., Santos-Ocaña, C. (2011). Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p. Biochem J 440: 107-114. (Publication) (All modifications)
[114, Phos]Busso, C., Ferreira-Júnior, J.R., Paulela, J.A., Bleicher, L., Demasi, M., Barros, M.H. (2015). Coq7p relevant residues for protein activity and stability. Biochimie 119: 92-102. (Publication) (All modifications)