Basic Information

NameMaintenance of mitochondrial morphology protein 1 (Mitochondrial outer membrane protein MMM1) (Yeast mitochondrial escape protein 6)
Uniprot IDP41800
Systematic gene nameYLL006W
Standard gene nameMMM1
Gene namesMMM1 YME6 YLL006W L1357
Description from SGDYLL006W MMM1 SGDID:S000003929, Chr XII from 136586-137866, Genome Release 64-3-1, Verified ORF, "ER integral membrane protein, ERMES complex subunit; ERMES links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; required for mitophagy; ERMES complex is often co-localized with peroxisomes and with concentrated areas of pyruvate dehydrogenase"
Protein length426
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MTDSENESTE TDSLMTFDDY ISKELPEHLQ RLIMENLKGS TTNDLKQTSN
NSEFNVSKNG SFKGLDDAIQ ALQMQSVLHP SSLGSLATSS KFSGWSFAQG
FFVGQLSIVL LFIFFLKFFI FSDEPSKSKN PKPAASRHRS KFKEYPFISR
EFLTSLVRKG AKQHYELNEE AENEHLQELA LILEKTYYNV DVHPAESLDW
FNVLVAQIIQ QFRSEAWHRD NILHSLNDFI GRKSPDLPEY LDTIKITELD
TGDDFPIFSN CRIQYSPNSG NKKLEAKIDI DLNDHLTLGV ETKLLLNYPK
PGIAALPINL VVSIVRFQAC LTVSLTNAEE FASTSNGSSS ENGMEGNSGY
FLMFSFSPEY RMEFEIKSLI GSRSKLENIP KIGSVIEYQI KKWFVERCVE
PRFQFVRLPS MWPRSKNTRE EKPTEL

Legend

  • X Glycosylation
  • X Ubiquitination

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[50, Glyc]Zielinska, D.F.,  Gnad, F.,  Schropp, K.,  Wiśniewski, J.R.,  Mann, M. (2012). Mapping N-glycosylation sites across seven evolutionarily distant species reveals a divergent substrate proteome despite a common core machinery. Mol Cell 46: 542-548. (Publication) (All modifications)
[55, Glyc]Zielinska, D.F.,  Gnad, F.,  Schropp, K.,  Wiśniewski, J.R.,  Mann, M. (2012). Mapping N-glycosylation sites across seven evolutionarily distant species reveals a divergent substrate proteome despite a common core machinery. Mol Cell 46: 542-548. (Publication) (All modifications)
[233, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[422, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)