Basic Information
Name | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein QRI7) (tRNA threonylcarbamoyladenosine biosynthesis protein QRI7) |
Uniprot ID | P43122 |
Systematic gene name | YDL104C |
Standard gene name | QRI7 |
Gene names | QRI7 YDL104C D2366 |
Description from SGD | YDL104C QRI7 SGDID:S000002262, Chr IV from 274876-273653, Genome Release 64-3-1, reverse complement, Verified ORF, "Protein involved in threonylcarbamoyl adenosine biosynthesis; Sua5p and Qri7p are necessary and sufficient for RNA t6A modification in vitro; highly conserved mitochondrial protein; essential for t6A modification of mitochondrial tRNAs that decode ANN codons; similar to Kae1p and E. coli YgjD, both of which are also required for tRNA t6A modification; when directed to the cytoplasm, complements the essential function of Kae1p in the KEOPS complex" |
Protein length | 407 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MISIKGTGRF LLDNYRIWQR RAFNRPIQLR KGYKVLAIET SCDDTCVSVL
DRFSKSAAPN VLANLKDTLD SIDEGGIIPT KAHIHHQARI GPLTERALIE
SNAREGIDLI CVTRGPGMPG SLSGGLDFAK GLAVAWNKPL IGVHHMLGHL
LIPRMGTNGK VPQFPFVSLL VSGGHTTFVL SRAIDDHEIL CDTIDIAVGD
SLDKCGRELG FKGTMIAREM EKFINQDIND QDFALKLEMP SPLKNSASKR
NMLSFSFSAF ITALRTNLTK LGKTEIQELP EREIRSIAYQ VQESVFDHII
NKLKHVLKSQ PEKFKNVREF VCSGGVSSNQ RLRTKLETEL GTLNSTSFFN
FYYPPMDLCS DNSIMIGWAG IEIWESLRLV SDLDICPIRQ WPLNDLLSVD
GWRTDQL
DRFSKSAAPN VLANLKDTLD SIDEGGIIPT KAHIHHQARI GPLTERALIE
SNAREGIDLI CVTRGPGMPG SLSGGLDFAK GLAVAWNKPL IGVHHMLGHL
LIPRMGTNGK VPQFPFVSLL VSGGHTTFVL SRAIDDHEIL CDTIDIAVGD
SLDKCGRELG FKGTMIAREM EKFINQDIND QDFALKLEMP SPLKNSASKR
NMLSFSFSAF ITALRTNLTK LGKTEIQELP EREIRSIAYQ VQESVFDHII
NKLKHVLKSQ PEKFKNVREF VCSGGVSSNQ RLRTKLETEL GTLNSTSFFN
FYYPPMDLCS DNSIMIGWAG IEIWESLRLV SDLDICPIRQ WPLNDLLSVD
GWRTDQL
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
No sources available.