Basic Information

NameER-localized J domain-containing protein 5
Uniprot IDP43613
Systematic gene nameYFR041C
Standard gene nameERJ5
Gene namesERJ5 YFR041C
Description from SGDYFR041C ERJ5 SGDID:S000001937, Chr VI from 238255-237368, Genome Release 64-3-1, reverse complement, Verified ORF, "Type I membrane protein with a J domain; required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response"
Protein length295
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MNGYWKPALV VLGLVSLSYA FTTIETEIFQ LQNEISTKYG PDMNFYKFLK
LPKLQNSSTK EITKNLRKLS KKYHPDKNPK YRKLYERLNL ATQILSNSSN
RKIYDYYLQN GFPNYDFHKG GFYFSRMKPK TWFLLAFIWI VVNIGQYIIS
IIQYRSQRSR IENFISQCKQ QDDTNGLGVK QLTFKQHEKD EGKSLVVRFS
DVYVVEPDGS ETLISPDTLD KPSVKNCLFW RIPASVWNMT FGKSVGSAGK
EEIITDSKKY DGNQTKKGNK VKKGSAKKGQ KKMELPNGKV IYSRK

Legend

  • X Ubiquitination

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[169, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)