Basic Information
Name | Phosphatidylinositol transfer protein SFH5 (PITP SFH5) (SEC14 homolog 5) |
Uniprot ID | P47008 |
Systematic gene name | YJL145W |
Standard gene name | SFH5 |
Gene names | SFH5 YJL145W J0644 |
Description from SGD | YJL145W SFH5 SGDID:S000003681, Chr X from 145160-146044, Genome Release 64-3-1, Verified ORF, "Unusual phosphatidylinositol transfer protein (PITP) that binds heme; similar to Sec14p; founding member of conserved class of fungal hemoproteins; exhibits PI- but not PC-transfer activity; localizes to peripheral endoplasmic reticulum, cytosol, and microsomes; partially relocalizes to plasma membrane upon DNA replication stress" |
Protein length | 294 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MKFDNDSEKQ VFDKLKKAIP GIIKEKCAGY DELYGYKLNP EGLTQEEVDK
YYDEKIADRL TYKLCKAYQF EYSTIVQNLI DILNWRREFN PLSCAYKEVH
NTELQNVGIL TFDANGDANK KAVTWNLYGQ LVKKKELFQN VDKFVRYRIG
LMEKGLSLLD FTSSDNNYMT QVHDYKGVSV WRMDSDIKNC SKTVIGIFQK
YYPELLYAKY FVNVPTVFGW VYDLIKKFVD ETTRKKFVVL TDGSKLGQYL
KDCPYEGYGG KDKKNNLTKQ NVTNVHPTEY GLYILQKQII EDVE
YYDEKIADRL TYKLCKAYQF EYSTIVQNLI DILNWRREFN PLSCAYKEVH
NTELQNVGIL TFDANGDANK KAVTWNLYGQ LVKKKELFQN VDKFVRYRIG
LMEKGLSLLD FTSSDNNYMT QVHDYKGVSV WRMDSDIKNC SKTVIGIFQK
YYPELLYAKY FVNVPTVFGW VYDLIKKFVD ETTRKKFVVL TDGSKLGQYL
KDCPYEGYGG KDKKNNLTKQ NVTNVHPTEY GLYILQKQII EDVE
Legend
- X Ubiquitination
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[17, Ubi] | Back, S., Gorman, A.W., Vogel, C., Silva, G.M. (2019). Site-specific K63 ubiquitinomics provides insights into translation regulation under stress. Journal of Proteome Research 18(1): 309-318. (Publication) (All modifications) |
[17, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |
[50, Ubi] | Swaney, D.L., Beltrao, P., Starita, L., Guo, A., Rush, J., Fields, S., Krogan, N.J., Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications) |