Basic Information

NameMitochondrial import inner membrane translocase subunit TIM54
Uniprot IDP47045
Systematic gene nameYJL054W
Standard gene nameTIM54
Gene namesTIM54 YJL054W J1150
Description from SGDYJL054W TIM54 SGDID:S000003590, Chr X from 334265-335701, Genome Release 64-3-1, Verified ORF, "Component of the mitochondrial TIM22 complex; involved in insertion of polytopic proteins into the inner membrane"
Protein length478
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSSESGKPIA KPIRKPGYTN PALKALGIPA LRLPSRNWMI FWSVLTVSIG
GIAYDKYKQR QILSHATDLV KPLAEESMEV DKVPRKITVF IAPPPNDYLE
SSLKVWRRYV KPVLYYAGLD YELVQEDRQG IIRTNVANRI RELRKEILAS
TDGQPVKEPN QTVAKPSGSS TSKISSLLPF NKIIQDPAEE DDSFDPEIGK
KFKENFDWRN VIGIFYTMPK PKHIISEDAL TKDPILSGGV ICLGRGAYKE
YIAGIHEGLL GPIEKTEKTG STEPKMTGVV EANQIESKVS ESGATELVDA
EKETALEEAK VQDDLKVDEE NSSEDSQKFL KPFISSDQYP DLQIASELQT
PNGEFIRNPN TNIPLLINQP LLVIPIPNLI GFTTIPRRIH RFYQKRFYVE
DVCSSVVNCV RQTRIRPFDI AKDIDLAKDE EKDWPQNWVK QGKEKNSEWT
QELVCDPRIT KHMFVYEKPP KEEPESDI

Legend

  • X Phoshorylation
  • X SUMOylation
  • X K-benzoylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[2, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[3, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[173, SUMO]Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications)
[182, SUMO]Paasch, F., den Brave, F., Psakhye, I., Pfander, B., Jentsch, S. (2018). Failed mitochondrial import and impaired proteostasis trigger SUMOylation of mitochondrial proteins. J Biol Chem 293: 599-609. (Publication) (All modifications)
[220, K-bz]Wang, D., Yan, F., Wu, P., Ge, K., Li, M., Li, T., Gao, Y., Peng, C., Chen, Y. (2022). Global profiling of regulatory elements in the histone benzoylation pathway. Nature Communications 13(1):1369 (Publication) (All modifications)
[304, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[304, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)