Basic Information

NameMEMO1 family protein MHO1 (Memo-homolog 1)
Uniprot IDP47085
Systematic gene nameYJR008W
Standard gene nameMHO1
Gene namesMHO1 YJR008W J1431 YJR83.9
Description from SGDYJR008W MHO1 SGDID:S000003768, Chr X from 452430-453446, Genome Release 64-3-1, Verified ORF, "Protein of unknown function; inhibits haploid invasive growth when overexpressed; synthetically lethal with phospholipase C (PLC1); expression induced by mild heat-stress on a non-fermentable carbon source, upon entry into stationary phase and upon nitrogen deprivation; repressed by inosine and choline in an Opi1p-dependent manner; highly conserved from bacteria to human; Memo, the human homolog, is an ErbB2 interacting protein with an essential function in cell motility"
Protein length338
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSIRPATHAG SWYSNRAQEL SQQLHTYLIK STLKGPIHNA RIIICPHAGY
RYCGPTMAYS YASLDLNRNV KRIFILGPSH HIYFKNQILV SAFSELETPL
GNLKVDTDLC KTLIQKEYPE NGKKLFKPMD HDTDMAEHSL EMQLPMLVET
LKWREISLDT VKVFPMMVSH NSVDVDRCIG NILSEYIKDP NNLFIVSSDF
CHWGRRFQYT GYVGSKEELN DAIQEETEVE MLTARSKLSH HQVPIWQSIE
IMDRYAMKTL SDTPNGERYD AWKQYLEITG NTICGEKPIS VILSALSKIR
DAGPSGIKFQ WPNYSQSSHV TSIDDSSVSY ASGYVTIG

Legend

  • X Phoshorylation
  • X Ubiquitination

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


Use imported representation

Loading structure from server... It may take a while.

If you believe something went wrong, please make sure PDB ID is correct.
Please also make sure that WebGL is enabled in your browser.

References

[2, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[11, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[79, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[83, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[258, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)