Basic Information

NameBax inhibitor 1 (BH3 domain-containing protein BXI1)
Uniprot IDP48558
Systematic gene nameYNL305C
Standard gene nameBXI1
Gene namesBXI1 YBH3 YNL305C N0405
Description from SGDYNL305C BXI1 SGDID:S000005249, Chr XIV from 59791-58898, Genome Release 64-3-1, reverse complement, Verified ORF, "Protein involved in apoptosis; variously described as containing a BCL-2 homology (BH3) domain or as a member of the BAX inhibitor family; reported to promote apoptosis under some conditions and to inhibit it in others; localizes to ER and vacuole; may link the unfolded protein response to apoptosis via regulation of calcium-mediated signaling; translocates to mitochondria under apoptosis-inducing conditions in a process involving Mir1p and Cor1p"
Protein length297
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSGPPPPYEE QSSHLYGQPA SSQDGNAFIP EDFKYSTVVI SCEPIIRQRF
MHKVYSLLSC QLLASLSFCY WASVSTSLQN FIMSHIALFY ICMVVSLVSC
IWLAVSPRPE DYEASVPEPL LTGSSEEPAQ EQRRLPWYVL SSYKQKLTLL
SIFTLSEAYC LSLVTLAYDK DTVLSALLIT TIVVVGVSLT ALSERFENVL
NSATSIYYWL NWGLWIMIGM GLTALLFGWN THSSKFNLLY GWLGAILFTA
YLFIDTQLIF RKVYPDEEVR CAMMLYLDIV NLFLSILRIL ANSNDDN

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[2, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[12, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[13, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[21, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[22, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)