Basic Information

NamerRNA methyltransferase 2, mitochondrial (EC 2.1.1.168) (21S rRNA (uridine(2791)-2'-O)-methyltransferase) (21S rRNA [Um2791] 2'-O-methyltransferase)
Uniprot IDP53123
Systematic gene nameYGL136C
Standard gene nameMRM2
Gene namesMRM2 YGL136C G2830
Description from SGDYGL136C MRM2 SGDID:S000003104, Chr VII from 253859-252897, Genome Release 64-3-1, reverse complement, Verified ORF, "Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ"
Protein length320
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MILVYNRIRS IISSSLGRIH VRYNSNSQNR WLNRQLKDPY TKEAKVQNLR
SRAAFKLMQI DDKYRLFSKN RTDQRILDLG YAPGAWSQVA RQRSSPNSMI
LGVDILPCEP PHGVNSIQAN ILAKRTHDLI RLFFSKHFQL NRHDDLHKDH
GYFQNMLEEE LTHVKDTELY REIFTSDDIY ETPNTNSTLI EREKFPVDVI
ISDMYEPWPQ TTGFWNNITN QAYFRMANTS GVSIRDHYQS IDLCDAALVT
AIDLLRPLGS FVCKLYTGEE ENLFKKRMQA VFTNVHKFKP DASRDESKET
YYIGLKKKRN VDKLDVFSNS

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[13, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[13, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[318, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[318, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)
[320, Phos]Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications)
[320, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)