Basic Information
Name | tRNA pseudouridine(27/28) synthase (EC 5.4.99.44) (tRNA pseudouridine synthase 2) (tRNA pseudouridylate synthase 2) (tRNA-uridine isomerase 2) |
Uniprot ID | P53167 |
Systematic gene name | YGL063W |
Standard gene name | PUS2 |
Gene names | PUS2 YGL063W |
Description from SGD | YGL063W PUS2 SGDID:S000003031, Chr VII from 383654-384766, Genome Release 64-3-1, Verified ORF, "Mitochondrial tRNA:pseudouridine synthase; acts at positions 27 and 28, but not at position 72; efficiently and rapidly targeted to mitochondria, specifically dedicated to mitochondrial tRNA modification; mutation also affects pseudouridylation of some nuclear-encoded mRNAs; PUS2 has a paralog, PUS1, that arose from the whole genome duplication" |
Protein length | 370 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MLLGYCGSGY YGMQYNPPHK TIEGEILTKL FDVGAISEEN SLAPKKNSFM
AAARTDKGVH AMLNLLSLKI TLREDTVAKL NAALPPEIRV WGIQPVNKKF
NARSACDSRW YQYLIPEFIL IGPPRSSLLH RNVGGCYRED GSQEVWDTFL
EQTRGRFSGD ELCRLQDTAQ KLSESDPLVQ DYVGLLSGTL SGYCLSPSKL
DAFEAAMQEY VGTHNFHNFT TGKLWGDPSA QRHIKKVVVS QASPGWICVR
IHGQSFMLHQ IRRMVALAVL AARCQLPPNI VRNYFNAGPR KYIPRAPAQG
LLLEGPVFDG YNTKLRNLLY CEIRPDDITL ERMCRFRERQ ICTAIAHEET
QRHVFCHFVR QMNRLATPLI
AAARTDKGVH AMLNLLSLKI TLREDTVAKL NAALPPEIRV WGIQPVNKKF
NARSACDSRW YQYLIPEFIL IGPPRSSLLH RNVGGCYRED GSQEVWDTFL
EQTRGRFSGD ELCRLQDTAQ KLSESDPLVQ DYVGLLSGTL SGYCLSPSKL
DAFEAAMQEY VGTHNFHNFT TGKLWGDPSA QRHIKKVVVS QASPGWICVR
IHGQSFMLHQ IRRMVALAVL AARCQLPPNI VRNYFNAGPR KYIPRAPAQG
LLLEGPVFDG YNTKLRNLLY CEIRPDDITL ERMCRFRERQ ICTAIAHEET
QRHVFCHFVR QMNRLATPLI
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
No sources available.