Basic Information
Name | tRNA pseudouridine(31) synthase (EC 5.4.99.42) (Pseudouridine synthase 6) (Pseudouridylate synthase 6) (Uracil hydrolyase) (tRNA pseudouridine 31 synthase) (PSI31 synthase) |
Uniprot ID | P53294 |
Systematic gene name | YGR169C |
Standard gene name | PUS6 |
Gene names | PUS6 YGR169C |
Description from SGD | YGR169C PUS6 SGDID:S000003401, Chr VII from 835903-834689, Genome Release 64-3-1, reverse complement, Verified ORF, "tRNA:pseudouridine synthase; catalyzes the conversion of uridine to pseudouridine at position 31 in cytoplasmic and mitochondrial tRNAs; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability" |
Protein length | 404 |
Download | sequence (fasta, from Uniprot), modifications (csv format) |
Database links | Uniprot, SGD, TheCellVision.org, FungiDB |
Sequence
MSTIKVIEVY TQNGLRKVRP YYNRRSAFVK GRWLGKLLID VLVSEFKLRP
RAYYLDQIRK GTYRLIRDGV PLVPDHLMTT IIKNHDVLET TTHKHEPPVK
QWCSQEVEAE DLPGRIAGFN IVFEDESILV IDKPSGIPVH PTGQFYQNTI
TELLKLHGVD ALPCYRLDKI TSGLLILAKN SQSAGEIQKS IRSRDMIKIY
LARVKGRFPH SELILDNENA AETTFEDTSK VTVEMTPIYS IDPKRQFPVG
LSTSKDAITK FYPIRYFSHA DETVVACKPI TGRTHQIRIH LARLGHPIVN
DSVYCSHITK YPERLKFITQ FPRWENQQDL DAEELKVRFQ KFVDETKNNC
RTMETFCPEC HTVDLKDPVL SDLELWLHAW KYEEINGKFK FKTDLPKWAQ
LDNS
RAYYLDQIRK GTYRLIRDGV PLVPDHLMTT IIKNHDVLET TTHKHEPPVK
QWCSQEVEAE DLPGRIAGFN IVFEDESILV IDKPSGIPVH PTGQFYQNTI
TELLKLHGVD ALPCYRLDKI TSGLLILAKN SQSAGEIQKS IRSRDMIKIY
LARVKGRFPH SELILDNENA AETTFEDTSK VTVEMTPIYS IDPKRQFPVG
LSTSKDAITK FYPIRYFSHA DETVVACKPI TGRTHQIRIH LARLGHPIVN
DSVYCSHITK YPERLKFITQ FPRWENQQDL DAEELKVRFQ KFVDETKNNC
RTMETFCPEC HTVDLKDPVL SDLELWLHAW KYEEINGKFK FKTDLPKWAQ
LDNS
Legend
- X Phoshorylation
Structure
Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.
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References
[183, Phos] | Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications) |
[273, Phos] | Bai Y, Chen B, Li M, et al (2017) FPD: A comprehensive phosphorylation database in fungi. Fungal Biology 121:869–875. (Publication) (All modifications) |
[273, Phos] | Albuquerque, C.P., Smolka, M.B., Payne, S.H., Bafna, V., Eng, J., Zhou, H. (2008). A multidimensional chromatography technology for in-depth phosphoproteome analysis. Molecular and Cellular Proteomics 7(7):1389-1396. (Publication) (All modifications) |
[273, Phos] | Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications) |