P53311 y-mtPTM: Yeast Mitochondrial PTM Database

Basic Information

Name	Mitochondrial pyruvate carrier 3 (MPC3) (Protein FMP43)
Uniprot ID	P53311
Systematic gene name	YGR243W
Standard gene name	MPC3
Gene names	MPC3 FMP43 YGR243W G8620
Description from SGD	YGR243W MPC3 SGDID:S000003475, Chr VII from 977336-977776, Genome Release 64-3-1, Verified ORF, "Highly conserved subunit of the mitochondrial pyruvate carrier (MPC); expressed during growth on nonfermentable carbon sources, and heterodimerizes with Mpc1p to form the respiratory isoform of MPC; MPC localizes to the mitochondrial inner membrane and mediates pyruvate uptake; MPC3 paralog, MPC2, heterodimerizes with Mpc1p to form the fermentative MPC isoform; protein abundance increases in response to DNA replication stress"
Protein length	146
Download	sequence (fasta, from Uniprot), modifications (csv format)
Database links	Uniprot, SGD, TheCellVision.org, FungiDB

Sequence

MSASAFNFAF RRFWNSETGP KTVHFWAPTL KWGLVFAGLN DIKRPVEKVS
GAQNLSLLAT ALIWTRWSFV IKPKNYLLAS VNFFLGCTAG YHLTRIANFR
IRNGDSFKQV IHYIIKGETP AAVAAKQTAS TSMNKGVIGT NPPITH

Structure

Structure visualized

Loading structure by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database. id="glmol01_src" style="display: none;"> -8.373 30.776 -38.064 1.00 48.56 N -7.183 29.898 -38.158 1.00 48.56 C -7.480 28.826 -39.199 1.00 48.56 C -8.508 28.175 -39.080 1.00 48.56 O -6.839 29.270 -36.797 1.00 48.56 C -6.426 30.314 -35.750 1.00 48.56 C -5.883 29.565 -34.196 1.00 48.56 S -5.844 31.019 -33.111 1.00 48.56 C -6.683 28.733 -40.269 1.00 48.01 N -7.008 27.932 -41.464 1.00 48.01 C -7.040 26.423 -41.174 1.00 48.01 C -6.103 25.893 -40.573 1.00 48.01 O -5.999 28.239 -42.580 1.00 48.01 C -6.320 27.467 -43.712 1.00 48.01 O -8.082 25.724 -41.641 1.00 61.17 N -8.245 24.268 -41.525 1.00 61.17 C -7.034 23.476 -42.068 1.00 61.17 C -6.738 22.371 -41.609 1.00 61.17 O -9.529 23.890 -42.277 1.00 61.17 C -6.278 24.074 -42.992 1.00 64.65 N -5.056 23.515 -43.573 1.00 64.65 C -3.932 23.335 -42.544 1.00 64.65 C -3.197 22.351 -42.611 1.00 64.65 O -4.567 24.428 -44.709 1.00 64.65 C -5.656 24.984 -45.424 1.00 64.65 O -3.816 24.238 -41.561 1.00 65.71 N -2.780 24.166 -40.526 1.00 65.71 C -3.042 23.022 -39.532 1.00 65.71 C -2.113 22.315 -39.144 1.00 65.71 O -2.688 25.524 -39.819 1.00 65.71 C -4.312 22.785 -39.182 1.00 62.06 N -4.710 21.650 -38.346 1.00 62.06 C -4.443 20.314 -39.050 1.00 62.06 C -3.868 19.407 -38.456 1.00 62.06 O -6.189 21.792 -37.960 1.00 62.06 C -6.681 20.684 -37.048 1.00 62.06 C -7.368 19.575 -37.581 1.00 62.06 C -6.431 20.749 -35.664 1.00 62.06 C -7.803 18.541 -36.734 1.00 62.06 C -6.871 19.716 -34.817 1.00 62.06 C -7.557 18.612 -35.352 1.00 62.06 C -4.784 20.204 -40.339 1.00 68.37 N -4.560 18.981 -41.116 1.00 68.37 C -3.056 18.681 -41.297 1.00 68.37 C -2.627 17.534 -41.169 1.00 68.37 O -5.326 19.123 -42.445 1.00 68.37 C -5.717 17.798 -43.084 1.00 68.37 C -6.779 17.800 -43.855 1.00 68.37 N -5.097 16.757 -42.923 1.00 68.37 O -2.225 19.710 -41.506 1.00 71.93 N -0.769 19.554 -41.577 1.00 71.93 C -0.156 19.126 -40.235 1.00 71.93 C 0.625 18.174 -40.193 1.00 71.93 O -0.138 20.856 -42.083 1.00 71.93 C 1.363 20.752 -42.274 1.00 71.93 C 2.244 21.238 -41.288 1.00 71.93 C 1.881 20.153 -43.438 1.00 71.93 C 3.635 21.135 -41.472 1.00 71.93 C 3.272 20.050 -43.620 1.00 71.93 C 4.148 20.543 -42.639 1.00 71.93 C -0.547 19.771 -39.130 1.00 70.09 N -0.098 19.393 -37.791 1.00 70.09 C -0.529 17.961 -37.429 1.00 70.09 C 0.278 17.188 -36.915 1.00 70.09 O -0.631 20.421 -36.787 1.00 70.09 C -1.760 17.572 -37.777 1.00 69.43 N -2.280 16.220 -37.567 1.00 69.43 C -1.513 15.166 -38.374 1.00 69.43 C -1.135 14.133 -37.826 1.00 69.43 O -3.773 16.205 -37.911 1.00 69.43 C -4.460 14.886 -37.625 1.00 69.43 C -4.758 13.995 -38.674 1.00 69.43 C -4.833 14.565 -36.307 1.00 69.43 C -5.467 12.810 -38.409 1.00 69.43 C -5.540 13.379 -36.042 1.00 69.43 C -5.881 12.517 -37.098 1.00 69.43 C -1.208 15.426 -39.655 1.00 65.82 N -0.393 14.519 -40.486 1.00 65.82 C 1.048 14.410 -39.992 1.00 65.82 C 1.598 13.312 -39.986 1.00 65.82 O -0.419 14.968 -41.953 1.00 65.82 C -1.752 14.632 -42.634 1.00 65.82 C -1.697 15.023 -44.114 1.00 65.82 C -2.949 14.664 -44.805 1.00 65.82 N -3.077 14.021 -45.957 1.00 65.82 C -2.053 13.620 -46.661 1.00 65.82 N1+ -4.261 13.765 -46.436 1.00 65.82 N 1.653 15.519 -39.553 1.00 66.53 N 3.007 15.525 -38.976 1.00 66.53 C 3.060 14.781 -37.641 1.00 66.53 C 4.030 14.077 -37.394 1.00 66.53 O 3.517 16.971 -38.877 1.00 66.53 C 4.985 17.034 -38.421 1.00 66.53 C 5.574 18.428 -38.676 1.00 66.53 C 6.940 18.562 -38.125 1.00 66.53 N 8.087 18.261 -38.715 1.00 66.53 C 8.147 17.753 -39.915 1.00 66.53 N1+ 9.216 18.467 -38.097 1.00 66.53 N 2.013 14.883 -36.826 1.00 68.06 N 1.859 14.097 -35.602 1.00 68.06 C 1.671 12.597 -35.893 1.00 68.06 C 2.312 11.767 -35.257 1.00 68.06 O 0.690 14.681 -34.799 1.00 68.06 C 0.393 13.927 -33.522 1.00 68.06 C -0.691 13.030 -33.468 1.00 68.06 C 1.218 14.102 -32.397 1.00 68.06 C -0.951 12.316 -32.286 1.00 68.06 C 0.960 13.383 -31.217 1.00 68.06 C -0.125 12.492 -31.163 1.00 68.06 C 0.855 12.234 -36.891 1.00 63.70 N 0.615 10.833 -37.272 1.00 63.70 C 1.809 10.124 -37.922 1.00 63.70 C 1.909 8.900 -37.816 1.00 63.70 O -0.606 10.744 -38.198 1.00 63.70 C -1.850 10.327 -37.490 1.00 63.70 C -2.886 11.124 -37.164 1.00 63.70 C -2.178 9.007 -36.965 1.00 63.70 C -3.458 9.071 -36.342 1.00 63.70 C -1.503 7.769 -36.927 1.00 63.70 C -3.839 10.384 -36.493 1.00 63.70 N -4.053 7.960 -35.728 1.00 63.70 C -2.086 6.646 -36.306 1.00 63.70 C -3.358 6.740 -35.713 1.00 63.70 C 2.686 10.870 -38.597 1.00 63.27 N 3.844 10.335 -39.317 1.00 63.27 C 5.190 10.599 -38.617 1.00 63.27 C 6.225 10.330 -39.221 1.00 63.27 O 3.830 10.873 -40.762 1.00 63.27 C 2.713 10.315 -41.626 1.00 63.27 C 2.292 11.059 -42.622 1.00 63.27 N 2.223 9.205 -41.463 1.00 63.27 O 5.224 11.136 -37.388 1.00 63.66 N 6.503 11.298 -36.680 1.00 63.66 C 7.069 9.938 -36.247 1.00 63.66 C 6.317 9.017 -35.923 1.00 63.66 O 6.422 12.300 -35.514 1.00 63.66 C 5.906 11.729 -34.333 1.00 63.66 O 8.400 9.814 -36.197 1.00 59.05 N 9.108 8.614 -35.702 1.00 59.05 C 8.766 8.263 -34.244 1.00 59.05 C 8.990 7.144 -33.798 1.00 59.05 O 10.624 8.830 -35.822 1.00 59.05 C 11.125 8.612 -37.256 1.00 59.05 C 12.621 8.917 -37.422 1.00 59.05 C 13.177 8.470 -38.447 1.00 59.05 O 13.173 9.638 -36.559 1.00 59.05 O1- 8.172 9.201 -33.506 1.00 57.08 N 7.649 9.043 -32.141 1.00 57.08 C 6.122 9.186 -32.082 1.00 57.08 C 5.551 9.486 -31.033 1.00 57.08 O 8.346 10.029 -31.195 1.00 57.08 C 9.823 9.676 -31.011 1.00 57.08 C 8.292 11.344 -31.719 1.00 57.08 O 5.447 8.996 -33.217 1.00 55.42 N 4.015 9.222 -33.389 1.00 55.42 C 3.141 8.116 -32.784 1.00 55.42 C 3.652 7.099 -32.296 1.00 55.42 O 1.803 8.252 -32.864 1.00 61.42 N 0.827 7.337 -32.260 1.00 61.42 C 0.857 5.907 -32.824 1.00 61.42 C 0.116 5.047 -32.360 1.00 61.42 O -0.537 8.008 -32.470 1.00 61.42 C -0.322 8.832 -33.736 1.00 61.42 C 1.119 9.305 -33.595 1.00 61.42 C 1.712 5.619 -33.810 1.00 58.39 N 1.973 4.260 -34.302 1.00 58.39 C 3.041 3.513 -33.494 1.00 58.39 C 3.232 2.323 -33.713 1.00 58.39 O 2.336 4.312 -35.793 1.00 58.39 C 1.158 4.800 -36.648 1.00 58.39 C 1.520 4.760 -38.135 1.00 58.39 C 0.353 5.266 -38.987 1.00 58.39 C 0.746 5.391 -40.412 1.00 58.39 N1+ 3.739 4.178 -32.571 1.00 63.26 N 4.843 3.571 -31.813 1.00 63.26 C 4.421 3.149 -30.405 1.00 63.26 C 3.689 3.855 -29.707 1.00 63.26 O 6.083 4.475 -31.774 1.00 63.26 C 6.532 4.892 -33.171 1.00 63.26 C 5.849 5.630 -31.002 1.00 63.26 O 4.934 2.004 -29.939 1.00 61.52 N 4.755 1.544 -28.547 1.00 61.52 C 5.344 2.530 -27.535 1.00 61.52 C 4.865 2.616 -26.409 1.00 61.52 O 5.355 0.141 -28.321 1.00 61.52 C 4.563 -0.915 -29.097 1.00 61.52 C 6.837 0.045 -28.714 1.00 61.52 C 6.331 3.331 -27.948 1.00 67.26 N 6.928 4.385 -27.132 1.00 67.26 C 5.989 5.572 -26.884 1.00 67.26 C 6.146 6.230 -25.860 1.00 67.26 O 8.236 4.850 -27.782 1.00 67.26 C 9.299 3.783 -27.764 1.00 67.26 C 9.773 3.075 -28.835 1.00 67.26 C 9.969 3.330 -26.649 1.00 67.26 N 10.823 2.369 -27.038 1.00 67.26 C 10.725 2.172 -28.359 1.00 67.26 N 5.000 5.817 -27.753 1.00 63.75 N 3.930 6.791 -27.516 1.00 63.75 C 2.818 6.214 -26.629 1.00 63.75 C 2.383 6.845 -25.664 1.00 63.75 O 3.356 7.254 -28.863 1.00 63.75 C 2.198 8.218 -28.708 1.00 63.75 C 0.873 7.739 -28.664 1.00 63.75 C 2.450 9.592 -28.553 1.00 63.75 C -0.194 8.632 -28.468 1.00 63.75 C 1.383 10.484 -28.345 1.00 63.75 C 0.062 10.004 -28.300 1.00 63.75 C 2.369 4.988 -26.924 1.00 66.51 N 1.309 4.339 -26.148 1.00 66.51 C 1.748 3.965 -24.736 1.00 66.51 C 0.927 4.020 -23.827 1.00 66.51 O 0.769 3.117 -26.891 1.00 66.51 C -0.126 3.473 -28.030 1.00 66.51 C 0.207 3.431 -29.337 1.00 66.51 C -1.493 3.989 -27.979 1.00 66.51 C -1.932 4.230 -29.314 1.00 66.51 C -2.399 4.299 -26.939 1.00 66.51 C -0.857 3.871 -30.093 1.00 66.51 N -3.200 4.747 -29.611 1.00 66.51 C -3.678 4.817 -27.225 1.00 66.51 C -4.080 5.037 -28.555 1.00 66.51 C 3.024 3.641 -24.509 1.00 69.64 N 3.514 3.294 -23.179 1.00 69.64 C 3.273 4.427 -22.152 1.00 69.64 C 2.640 4.153 -21.133 1.00 69.64 O 4.965 2.793 -23.267 1.00 69.64 C 3.684 5.692 -22.381 1.00 68.57 N 3.298 6.830 -21.542 1.00 68.57 C 1.783 7.009 -21.388 1.00 68.57 C 1.311 7.191 -20.267 1.00 68.57 O 3.929 8.063 -22.199 1.00 68.57 C 5.144 7.499 -22.922 1.00 68.57 C 4.677 6.114 -23.351 1.00 68.57 C 1.017 6.913 -22.477 1.00 70.66 N -0.445 7.102 -22.463 1.00 70.66 C -1.156 6.055 -21.604 1.00 70.66 C -1.962 6.401 -20.743 1.00 70.66 O -0.989 7.078 -23.900 1.00 70.66 C -2.488 7.361 -23.975 1.00 70.66 C -0.334 8.085 -24.635 1.00 70.66 O -0.815 4.774 -21.764 1.00 70.34 N -1.360 3.675 -20.961 1.00 70.34 C -1.001 3.822 -19.481 1.00 70.34 C -1.811 3.526 -18.605 1.00 70.34 O -0.820 2.340 -21.502 1.00 70.34 C -1.399 1.920 -22.865 1.00 70.34 C -0.666 0.671 -23.355 1.00 70.34 C -2.894 1.607 -22.783 1.00 70.34 C 0.196 4.334 -19.190 1.00 68.18 N 0.644 4.586 -17.819 1.00 68.18 C -0.136 5.724 -17.148 1.00 68.18 C -0.459 5.601 -15.969 1.00 68.18 O 2.163 4.779 -17.845 1.00 68.18 C 2.878 3.405 -17.905 1.00 68.18 C 4.166 3.313 -18.747 1.00 68.18 C 5.332 2.650 -18.008 1.00 68.18 C 6.643 3.038 -18.583 1.00 68.18 N1+ -0.545 6.757 -17.890 1.00 72.65 N -1.527 7.742 -17.407 1.00 72.65 C -2.940 7.165 -17.287 1.00 72.65 C -3.684 7.566 -16.393 1.00 72.65 O -1.518 8.980 -18.305 1.00 72.65 C -0.405 9.925 -17.995 1.00 72.65 C 0.732 10.081 -18.708 1.00 72.65 C -0.311 10.857 -16.876 1.00 72.65 C 0.932 11.550 -16.973 1.00 72.65 C -1.154 11.188 -15.792 1.00 72.65 C 1.525 11.041 -18.109 1.00 72.65 N 1.323 12.526 -16.045 1.00 72.65 C -0.771 12.165 -14.853 1.00 72.65 C 0.461 12.833 -14.978 1.00 72.65 C -3.291 6.176 -18.113 1.00 74.46 N -4.535 5.416 -17.986 1.00 74.46 C -4.730 4.824 -16.587 1.00 74.46 C -5.832 4.908 -16.050 1.00 74.46 O -3.664 4.322 -15.945 1.00 68.37 N -3.748 3.808 -14.570 1.00 68.37 C -4.066 4.910 -13.546 1.00 68.37 C -4.845 4.682 -12.623 1.00 68.37 O -2.449 3.061 -14.200 1.00 68.37 C -2.577 2.237 -12.897 1.00 68.37 C -3.540 1.060 -13.056 1.00 68.37 C -1.225 1.669 -12.468 1.00 68.37 C -3.509 6.112 -13.730 1.00 70.10 N -3.789 7.278 -12.874 1.00 70.10 C -5.258 7.681 -12.995 1.00 70.10 C -5.943 7.834 -11.986 1.00 70.10 O -2.870 8.470 -13.221 1.00 70.10 C -3.114 9.660 -12.284 1.00 70.10 C -1.388 8.074 -13.147 1.00 70.10 C -5.773 7.787 -14.224 1.00 75.94 N -7.180 8.113 -14.463 1.00 75.94 C -8.136 7.023 -13.968 1.00 75.94 C -9.184 7.349 -13.414 1.00 75.94 O -7.410 8.388 -15.953 1.00 75.94 C -6.828 9.702 -16.432 1.00 75.94 C -7.344 10.916 -15.939 1.00 75.94 C -5.789 9.721 -17.381 1.00 75.94 C -6.813 12.140 -16.382 1.00 75.94 C -5.254 10.945 -17.818 1.00 75.94 C -5.765 12.154 -17.318 1.00 75.94 C -7.780 5.745 -14.125 1.00 71.64 N -8.567 4.631 -13.605 1.00 71.64 C -8.676 4.687 -12.071 1.00 71.64 C -9.777 4.565 -11.538 1.00 71.64 O -7.944 3.317 -14.089 1.00 71.64 C -7.565 4.959 -11.374 1.00 68.41 N -7.554 5.153 -9.921 1.00 68.41 C -8.425 6.328 -9.471 1.00 68.41 C -9.215 6.201 -8.538 1.00 68.41 O -8.359 7.455 -10.184 1.00 73.30 N -9.212 8.613 -9.902 1.00 73.30 C -10.701 8.331 -10.163 1.00 73.30 C -11.558 8.877 -9.470 1.00 73.30 O -8.735 9.815 -10.734 1.00 73.30 C -7.372 10.395 -10.311 1.00 73.30 C -6.966 11.493 -11.295 1.00 73.30 C -7.398 10.999 -8.905 1.00 73.30 C -11.037 7.486 -11.141 1.00 74.72 N -12.428 7.138 -11.433 1.00 74.72 C -13.066 6.296 -10.308 1.00 74.72 C -14.237 6.507 -9.978 1.00 74.72 O -12.495 6.448 -12.805 1.00 74.72 C -13.897 6.490 -13.386 1.00 74.72 C -14.136 7.340 -14.359 1.00 74.72 N -14.806 5.790 -12.984 1.00 74.72 O -12.289 5.426 -9.646 1.00 68.85 N -12.773 4.560 -8.553 1.00 68.85 C -13.142 5.330 -7.269 1.00 68.85 C -13.820 4.807 -6.382 1.00 68.85 O -11.760 3.436 -8.265 1.00 68.85 C -12.393 2.279 -7.467 1.00 68.85 C -13.494 1.821 -7.858 1.00 68.85 O -11.799 1.830 -6.461 1.00 68.85 O1- -12.814 6.627 -7.188 1.00 68.81 N -13.219 7.518 -6.085 1.00 68.81 C -14.743 7.498 -5.860 1.00 68.81 C -15.205 7.668 -4.727 1.00 68.81 O -12.688 8.951 -6.349 1.00 68.81 C -11.142 8.952 -6.257 1.00 68.81 C -13.303 9.980 -5.378 1.00 68.81 C -10.474 10.284 -6.623 1.00 68.81 C -15.541 7.236 -6.906 1.00 68.13 N -17.010 7.165 -6.821 1.00 68.13 C -17.533 5.936 -6.070 1.00 68.13 C -18.698 5.930 -5.672 1.00 68.13 O -17.614 7.232 -8.231 1.00 68.13 C -17.358 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