Basic Information

NameProbable family 17 glucosidase SCW4 (EC 3.2.1.-) (Soluble cell wall protein 4)
Uniprot IDP53334
Systematic gene nameYGR279C
Standard gene nameSCW4
Gene namesSCW4 YGR279C
Description from SGDYGR279C SCW4 SGDID:S000003511, Chr VII from 1049958-1048798, Genome Release 64-3-1, reverse complement, Verified ORF, "Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating; SCW4 has a paralog, SCW10, that arose from the whole genome duplication"
Protein length386
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MRLSNLIASA SLLSAATLAA PANHEHKDKR AVVTTTVQKQ TTIIVNGAAS
TPVAALEENA VVNSAPAAAT STTSSAASVA TAAASSSENN SQVSAAASPA
SSSAATSTQS SSSSQASSSS SSGEDVSSFA SGVRGITYTP YESSGACKSA
SEVASDLAQL TDFPVIRLYG TDCNQVENVF KAKASNQKVF LGIYYVDQIQ
DGVNTIKSAV ESYGSWDDVT TVSIGNELVN GNQATPSQVG QYIDSGRSAL
KAAGYTGPVV SVDTFIAVIN NPELCDYSDY MAVNAHAYFD KNTVAQDSGK
WLLEQIQRVW TACDGKKNVV ITESGWPSKG ETYGVAVPSK ENQKDAVSAI
TSSCGADTFL FTAFNDYWKA DGAYGVEKYW GILSNE

Legend

  • X Ubiquitination
  • X Glutathionylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[181, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[354, Glut]Rekstina, V.V., Sabirzyanova, T.A., Sabirzyanov, F.A., Adzhubei,, A.A., Tkachev, Y.V., Kudryashova, I.B., Snalina, N.E., Bykova, A.A., Alessenko, A.V., Ziganshin, R.H., Kuznetsov, S.A., Kalebina, T.S. (2020). The post-translational modifications, localization, and mode of attachment of non-covalently bound glucanosyltransglycosylases of yeast cell wall as a key to understanding their functioning. Int J Mol Sci 21: 8304. (Publication) (All modifications)