Basic Information

NametRNA-dihydrouridine(16/17) synthase [NAD(P)(+)] (EC 1.3.1.88) (tRNA-dihydrouridine synthase 1)
Uniprot IDP53759
Systematic gene nameYML080W
Standard gene nameDUS1
Gene namesDUS1 YML080W
Description from SGDYML080W DUS1 SGDID:S000004545, Chr XIII from 108806-110077, Genome Release 64-3-1, Verified ORF, "Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17"
Protein length423
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MTEPALSSAN NALMQKLTGR QLFDKIGRPT RIVAPMVDQS ELAWRILSRR
YGATLAYTPM LHAKLFATSK KYREDNWSSL DGSSVDRPLV VQFCANDPEY
LLAAAKLVED KCDAVDLNLG CPQGIAKKGH YGSFLMEEWD LIHNLINTLH
KNLKVPVTAK IRIFDDCEKS LNYAKMVLDA GAQFLTVHGR VREQKGQKTG
LANWETIKYL RDNLPKETVF FANGNILYPE DISRCMEHIG ADAVMSAEGN
LYNPGVFNVG QTKNKEKIFP RVDKIIREYF QIVKECQESK ASKTAMKSHF
FKILRPFLPH HTDIRSTLAT MNAKATWEEW EEQVVKPVEK VVQEIFEQPD
IAIKDEITIG EKQSWGGSYR TVPYWRCQPY FRPVNGITGD KRVMQGLIDE
SVNKKRKADV PLESADKKKD VKA

Legend

  • X Ubiquitination

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


Use imported representation

Loading structure from server... It may take a while.

If you believe something went wrong, please make sure PDB ID is correct.
Please also make sure that WebGL is enabled in your browser.

References

[169, Ubi]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)