Basic Information

NameCytochrome c1 heme lyase (CC1HL) (EC 4.4.1.-)
Uniprot IDQ00873
Systematic gene nameYKL087C
Standard gene nameCYT2
Gene namesCYT2 YKL087C
Description from SGDYKL087C CYT2 SGDID:S000001570, Chr XI from 277863-277189, Genome Release 64-3-1, reverse complement, Verified ORF, "Cytochrome c1 heme lyase; involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1; human homolog HCCS can complement yeast cyt2 null mutant"
Protein length224
Downloadsequence (fasta, from Uniprot), modifications (csv format)
Database linksUniprot, SGD, TheCellVision.org, FungiDB

Sequence

MMSSDQQGKC PVDEETKKLW LREHGNEAHP GATAPGNQLE CSANPQDNDK
TPEYHTTVDL SQSREVSTIP RTNSDRNWIY PSEKQFYEAM MKKNWDPNSD
DMKVVVPLHN SINERVWNYI KSWEDKQGGE ACGGIKLTNF KGDSKKLTPR
AWFRSRILHL AKPFDRHDWQ IDRCGKTVDY VIDFYSTDLN DANSQQQPLI
YLDVRPKLNS FEGFRLRFWK SLGF

Legend

  • X Phoshorylation

Structure

Structure visualized by GLmol written by biochem_fan. The structure was downloaded from the AlphaFold Protein Structure Database.


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References

[74, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[74, Phos]Swaney, D.L.,  Beltrao, P.,  Starita, L.,  Guo, A.,  Rush, J.,  Fields, S.,  Krogan, N.J.,  Villén, J. (2013). Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nature Methods 10(7): 676-682. (Publication) (All modifications)
[111, Phos]Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB (2021). In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Reports, e51121. (Publication) (All modifications)
[111, Phos]Renvoisé M, Bonhomme L, Davanture M, et al (2014) Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae. Journal of Proteomics 106:140–150. (Publication) (All modifications)
[111, Phos]Frankovsky, J., Vozáriková, V., Nosek, J., Tomáška, Ľ. (2021a). Mitochondrial protein phosphorylation in yeast revisited.Mitochondrion 57:148-162. (Publication) (All modifications)